Zapenia 100 mg (Tablet)
Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clozapine |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Schizophrenia treatment
- Parkinson's disease psychosis treatment
Pharmacology
- Dopamine receptor binding
- Effects on dopamine-mediated behaviors
- Limbic and striatal dopamine receptor activity
- Antagonistic action at adrenergic, cholinergic, histaminergic, and serotonergic receptors
Dosage & Administration
- Initial dosing for schizophrenia in adults over 16 years
- Initial dosing for elderly patients with schizophrenia
- Gradual incremental dosing for schizophrenia
- Usual dose range for schizophrenia
- Dosing for psychosis in Parkinson's disease
- Maximum dosage for psychosis in Parkinson's disease
Interaction
- Aggravation of myelosuppression
- Interaction with CNS active drugs and alcohol
- Possibility of orthostatic hypotension with benzodiazepines
- Protein displacement interactions
- Effects of concomitant Carbamazepine administration
- Interactions with various other drugs and enzymes
Contraindications
- Severe cardiac disorders
- Renal impairment
- History of neutropenia or agranulocytosis
- Alcoholic and toxic psychoses
- Uncontrolled epilepsy
- Breast-feeding
Side Effects
- Common side effects
- Less common side effects
Pregnancy & Lactation
- Use in pregnant women
- Animal studies
- Secretion in breast milk
Precautions & Warnings
- Abrupt medication stoppage
- Elderly patient susceptibility
- Agranulocytosis risk and WBC testing
- Cognitive and motor impairment
- Seizure risk and associated conditions
- Anticholinergic effects
- Hyperglycemia and hepatic disease caution
- Orthostatic hypotension and tachycardia
- Cardiomyopathy and thromboembolism associations
Overdose Effects
- Signs and symptoms
- Management and treatment
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Temperature and light restrictions
- Keep away from children