Fluanxol 40 mg/2 ml (Injection)

2 ml ampoule: ৳ 576.92 (10's pack: ৳ 5,769.20)

Medicine Details

Indications

  • Psychoses
  • Depression with or without anxiety

Pharmacology

  • Thioxanthene antipsychotic
  • Inhibits dopamine-mediated effects
  • Blocks postsynaptic dopamine receptors in the CNS

Dosage

  • Oral administration
  • Intramuscular administration
  • Dosage for adults and elderly
  • Maximum daily dosage
  • Dosage adjustment based on response

Administration

  • May be taken with or without food

Interaction

  • May potentiate adverse effects of drugs with antimuscarinic effects
  • Reduced efficacy of levodopa
  • Increases adverse extrapyramidal symptoms with dopamine antagonists

Contraindications

  • Hypersensitivity
  • Excitable and overactive patients
  • Mania
  • Porphyria
  • Preexisting CNS depression
  • Bone-marrow suppression
  • Phaeochromocytoma
  • Lactation

Side Effects

  • Rigidity
  • Tremors
  • Restlessness
  • Tardive dyskinesia
  • Insomnia
  • Dryness of mouth
  • Weight gain
  • Sexual dysfunction
  • Galactorrhea
  • Menstrual disturbances
  • Neuroleptic malignant syndrome

Pregnancy & Lactation

  • Category C drug
  • Adverse effects on the fetus
  • Benefit-risk consideration for use

Precautions & Warnings

  • Patients with convulsive disorders
  • Advanced hepatic, renal, CV or resp disease
  • Tasks requiring mental alertness
  • Elderly and debilitated patients
  • History of angle-closure glaucoma
  • Urinary retention
  • Prostatic hyperplasia
  • Breast cancer
  • Prolactin-dependent tumors
  • Parkinsonism
  • Myasthenia gravis
  • Pregnancy
  • Avoid direct sunlight

Therapeutic Class

  • SSRIs & related antidepressant drugs

Storage Conditions

  • Store below 25°C

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