Sentix 0.5 mg (Tablet)
Unit Price: ৳ 4.00 (5 x 10: ৳ 200.00)
Strip Price: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Flupentixol dihydrochloride |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Indications
- Psychoses
- Depression with or without anxiety
Pharmacology
- Thioxanthene antipsychotic
- Inhibits dopamine-mediated effects
- Blocks postsynaptic dopamine receptors in the CNS
Dosage
- Oral administration
- Intramuscular administration
- Dosage instructions for adults and elderly
- Max daily dosage
- Dosage adjustment based on response
Administration
- May be taken with or without food
Interaction
- May potentiate adverse effects of drugs with antimuscarinic effects
- Reduced efficacy of levodopa
- Increases adverse extrapyramidal symptoms with dopamine antagonists
Contraindications
- Hypersensitivity
- Excitable and overactive patients
- Mania
- Porphyria
- Preexisting CNS depression
- Bone-marrow suppression
- Phaeochromocytoma
- Lactation
Side Effects
- Rigidity
- Tremors
- Restlessness
- Tardive dyskinesia
- Insomnia
- Dryness of mouth
- Weight gain
- Sexual dysfunction
- Galactorrhoea
- Menstrual disturbances
- Potentially fatal: Neuroleptic malignant syndrome
Pregnancy & Lactation
- Category C: Potential risk to the foetus
- Drugs should be given only if potential benefit justifies potential risk to the foetus
Precautions & Warnings
- Convulsive disorders
- Advanced hepatic, renal, CV or resp disease
- Tasks requiring mental alertness
- Elderly and debilitated patients
- Neuroleptics withdrawal
- Angle-closure glaucoma
- Urinary retention
- Prostatic hyperplasia
- Breast cancer
- Parkinsonism
- Myasthenia gravis
- Avoid direct sunlight
Therapeutic Class
- SSRIs & related anti-depressant drugs
Storage Conditions
- Store below 25°C