Exuten 0.5 mg+10 mg (Tablet)

Unit Price: ৳ 3.51 (30's pack: ৳ 105.30)

Medicine Details

Category Details
Generic Flupentixol melitracen
Company Pharmadesh laboratories ltd

Title

  • Flupentixol and Melitracen Tablet

Categories

  • Combined anxiolytics & anti-depressant drugs

Description

  • Flupentixol and Melitracen tablet is indicated for Anxiety, Depression, Apathy, Psychogenic depression, Depressive neurosses, Masked depression, Psychosomatic affections accompanied by anxiety and apathy, Menopausal depressions, Dysphoria and depression in alcoholics and drug addicts.
  • This tablet consists of two well-known compounds: flupentixol (a neuroleptic with anxiolytic and antidepressant properties) and melitracen (a bipolar thymoleptic with activating properties).
  • Maximal serum concentration is reached in about 4 hours after oral administration of flupentixol and melitracen. The biological half-life of flupentixol is about 35 hours and that of melitracen is about 19 hours.
  • Adults: Usually 2 tablets orally daily in the morning and noon. In severe cases, the morning dose may be increased to 2 tablets.
  • Elderly patients: 1 tablet in the morning.
  • Maintenance dose: Usually 1 tablet orally in the morning. In cases of insomnia or severe restlessness, additional treatment with a sedative in the acute phase is recommended.
  • This tablet may enhance the response to alcohol, barbiturates and other CNS depressants. Simultaneous administration of MAO-inhibitors may cause hypertensive crises. Neuroleptics and thymoleptics reduce the antihypertensive effect of guanethidine and similar acting compounds and thymoleptics enhance the effects of adrenaline and noradrenaline.
  • Contraindications: The immediate recovery phase after myocardial infarction, Defects in bundle-branch conduction, Untreated narrow-angle glaucoma, Acute alcohol, barbiturate and opiate intoxications.
  • Side Effects: In the recommended doses side effects are rare. These could be transient restlessness and insomnia.
  • This tablet should preferably not be given during pregnancy and lactation.
  • If previously the patient has been treated with tranquilizers with sedative effect these should be withdrawn gradually.
  • In cases of overdosage, symptoms of intoxications by melitracen, especially of anticholinergic nature, dominate. More rarely extrapyramidal symptoms due to flupentixol occur. Symptomatic and supportive care is recommended.
  • Store at a temperature not exceeding 30°C in a dry place. Protect from light. Keep out of reach of children.
  • Exuten 0.5 mg Tablet consists of Flupentixol & Melitracen. This is used to treat in Anxiety, Depression, Apathym, Psychogenic depression, Depressive neurosses, Masked depression, Menopausal depressions.

Dimensions

    Color Options

      Functions

        Materials

          Technical Specifications

            Design Elements

              Usability Features

                Storage Conditions

                • Store at a temperature not exceeding 30°C in a dry place. Protect from light. Keep out of reach of children.

                Dosage & Administration

                • Adults: Usually 2 tablets orally daily in the morning and noon. In severe cases, the morning dose may be increased to 2 tablets.
                • Elderly patients: 1 tablet in the morning.
                • Maintenance dose: Usually 1 tablet orally in the morning. In cases of insomnia or severe restlessness, additional treatment with a sedative in the acute phase is recommended.

                Indications

                • Anxiety
                • Depression
                • Apathy
                • Psychogenic depression
                • Depressive neurosses
                • Masked depression
                • Psychosomatic affections accompanied by anxiety and apathy
                • Menopausal depressions
                • Dysphoria and depression in alcoholics and drug addicts

                Pharmacology

                • Consists of two well-known and well-proven compounds: flupentixol, a neuroleptic with anxiolytic and antidepressant properties of its own when given in small doses, and melitracen, a bipolar thymoleptic with activating properties in low doses.
                • In combination, the compounds render a preparation with antidepressant, anxiolytic, and activating properties.
                • Maximal serum concentration is reached in about 4 hours after oral administration of flupentixol and in about 4 hours after oral administration of melitracen.
                • The biological half-life of flupentixol is about 35 hours and that of melitracen is about 19 hours.
                • The combination of flupentixol and melitracen does not seem to influence the pharmacokinetic properties of the individual compounds.

                Interaction

                • This tablet may enhance the response to alcohol, barbiturates and other CNS depressants.
                • Simultaneous administration of MAO-inhibitors may cause hypertensive crises.
                • Neuroleptics and thymoleptics reduce the antihypertensive effect of guanethidine and similar acting compounds and thymoleptics enhance the effects of adrenaline and noradrenaline.

                Contraindications

                • The immediate recovery phase after myocardial infarction
                • Defects in bundle-branch conduction
                • Untreated narrow-angle glaucoma
                • Acute alcohol, barbiturate and opiate intoxications
                • This tablet should not be given to patients who have received an MAO-inhibitor within two weeks.
                • Not recommended for excitable or overactive patients since its activating effect may lead to exaggeration of these characteristics.

                Side Effects

                • In the recommended doses side effects are rare. These could be transient restlessness and insomnia.

                Pregnancy & Lactation

                • This tablet should preferably not be given during pregnancy and lactation.

                Precautions & Warnings

                • If previously the patient has been treated with tranquilizers with sedative effect these should be withdrawn gradually.

                Overdose Effects

                • In cases of overdosage the symptoms of intoxications by melitracen, especially of anticholinergic nature, dominate.
                • More rarely extrapyramidal symptoms due to flupentixol occur.
                • Symptomatic and supportive care, gastric lavage, and activated charcoal administration are recommended to manage overdosage.

                Therapeutic Class

                • Combined anxiolytics & anti-depressant drugs

                Common Questions & Answers

                • Exuten 0.5 mg Tablet consists of Flupentixol & Melitracen. This is used to treat in Anxiety, Depression, Apathym, Psychogenic depression, Depressive neurosses, Masked depression, Menopausal depressions.
                • Exuten 0.5 mg Tablet helps treat anxiety and depression.
                • Use caution while driving or doing anything that requires concentration as Exuten 0.5 mg Tablet can cause dizziness and sleepiness.
                • Avoid drinking alcohol while taking Exuten 0.5 mg Tablet because Exuten 0.5 mg Tablet can make drowsiness worse.
                • Exuten 0.5 mg Tablet can cause changes in your blood sugar levels. Monitor your blood sugar regularly.
                • Inform your doctor if you have liver disease, thyroid disorder, severe heart disease, or a urinary disorder.
                • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
                • Let your doctor know you are taking Exuten 0.5 mg Tablet before undergoing any surgical procedure.

                Related Brands