Frexit 0.5 mg+10 mg (Tablet)
Unit Price: ৳ 3.41 (30's pack: ৳ 102.27)
Medicine Details
| Category | Details |
|---|---|
| Generic | Flupentixol melitracen |
| Company | Asiatic laboratories ltd |
| Also available as |
Title and Category
- Frexit 0.5 mg Tablet
- Combined anxiolytics & anti-depressant drugs
Indications
- Anxiety
- Depression
- Apathy
- Psychogenic depression
- Depressive neurosses
- Masked depression
- Psychosomatic affections accompanied by anxiety and apathy
- Menopausal depressions
- Dysphoria and depression in alcoholics and drug addicts
Pharmacology
- Flupentixol-a neuroleptic with anxiolytic and antidepressant properties
- Melitracen-a bipolar thymoleptic with activating properties
- Antidepressant, anxiolytic, and activating properties
- Maximal serum concentration reached in about 4 hours after oral administration
Dosage & Administration
- Adults: Usually 2 tablets orally daily in the morning and noon
- Elderly patients: 1 tablet in the morning
- Maintenance dose: Usually 1 tablet orally in the morning
Interaction
- May enhance the response to alcohol, barbiturates, and other CNS depressants
- Simultaneous administration of MAO-inhibitors may cause hypertensive crises
- Neuroleptics and thymoleptics reduce the antihypertensive effect of guanethidine and similar acting compounds
Contraindications
- Immediate recovery phase after myocardial infarction
- Defects in bundle-branch conduction
- Untreated narrow-angle glaucoma
- Acute alcohol, barbiturate, and opiate intoxications
- Not recommended for excitable or overactive patients since its activating effect may lead to exaggeration of these characteristics
Side Effects
- Rare in recommended doses; transient restlessness and insomnia
Pregnancy & Lactation
- Preferably not given during pregnancy and lactation
Precautions & Warnings
- If previously treated with sedative tranquillizers, they should be withdrawn gradually
Overdose Effects
- Intoxications by melitracen dominate in overdosage
- Symptomatic and supportive care required
- Gastric lavage, activated charcoal administration, respiratory and cardiovascular support
- Epinephrine must not be used
- Convulsions may be treated with diazepam, extrapyramidal symptoms with biperiden
Storage Conditions
- Store at a temperature not exceeding 30°C in a dry place
- Protect from light
- Keep out of reach of children