Deprex 5 mg (Tablet)

Unit Price: ৳ 2.50 (5 x 10: ৳ 125.00)

Strip Price: ৳ 25.00

Medicine Details

Category	Details
Generic	Olanzapine
Company	Square pharmaceuticals plc
Also available as	Deprex 10 mg tablet

Title

Deprex Tablet

Description

Deprex is indicated for the acute and maintenance treatment of schizophrenia and related psychoses where positive and/or negative symptoms are prominent. It is also used for the treatment of acute manic or mixed episodes in bipolar disorder.

Color Options

White

Functions

Treatment of Schizophrenia
Treatment of Bipolar Disorder
Antipsychotic Treatment
Maintenance Therapy

Materials

Olanzapine

Technical Specifications

Affinities for Receptors:
- Serotonin 5HT2A/2C
- Serotonin 5HT3
- Serotonin 5HT6
- Dopamine D1
- Dopamine D2
- Dopamine D3
- Dopamine D4
- Dopamine D5
- Cholinergic Muscarinic Receptors M1-M5
- Alpha-1 Adrenergic
- Histamine H1
Maximum Daily Dose: 20 mg
Bioavailability: Highly Absorbed
Storage Conditions: Below 30°C temperature, away from light & moisture

Design Elements

Tablet Form

Usability Features

Can be Given Without Regard to Meals
Gradual tapering of the dose while discontinuing

Dimensions

Standard Tablet Dimensions

Dosage

Schizophrenia, Combination Therapy for Mania, Bipolar Disorder: 5-20 mg daily
Monotherapy for Mania: 5-20 mg daily

Administration

Olanzapine can be given without regard to meals

Interaction

Antagonizes:
- Levodopa
- Dopamine Agonists
Effect by Enzymes:
- CYP1A2
- Glucoronyl Transferase
Inducers:
- Omeprazole
- Rifampicin
Inhibitors: CYP1A2
Other Interactions:
- Carbamazepine
- Activated Charcoal
- Centrally Acting Drugs
- Alcohol

Contraindications

Hypersensitivity
Narrow-Angle Glaucoma

Side Effects

Somnolence
Weight Gain
Increased Appetite
Elevated Glucose Levels
Elevated Triglyceride Levels
Dizziness
Akathisia
Parkinson's Disease
Dyskinesia
Orthostatic Hypotension
Anticholinergic Effects
Constipation
Dry Mouth
Asthenia
Edema
Photosensitivity Reaction

Pregnancy & Lactation

Use in Pregnancy: If potential benefits justify potential risk
Teratogenecity: No report
Breastfeeding: Not recommended

Precautions & Warnings

Cautions for Use in Patients with:
- History of Seizures
- Low Leukocyte and/or Neutrophil Counts
- Hypereosinophilic Conditions
- Impaired Hepatic Function
- Hepatotoxic Medications
- Centrally Acting Drugs
- Medicines known to Increase QT Interval
Cautioned Activities: Operating hazardous machinery, including motor vehicles