Qpine 25 mg (Tablet)

Unit Price: ৳ 3.02 (10 x 10: ৳ 302.00)
Strip Price: ৳ 30.20

Medicine Details

Indications

  • Treatment of Acute and chronic psychoses
  • Treatment of schizophrenia
  • Bipolar disorder treatment
  • Manic episodes treatment
  • Depressive episodes treatment
  • Maintenance treatment of bipolar I disorder
  • Prevention of recurrence of manic, depressive or mixed episodes

Pharmacology

  • Atypical psychotropic agent
  • Belongs to dibenzothiazepine derivatives
  • Antagonist at multiple neurotransmitter receptors
  • Mechanism of action is unknown
  • Efficacy in schizophrenia through dopamine and serotonin antagonism

Dosage & Administration

  • Initial dosage titration
  • Twice daily administration
  • Administered with or without food
  • Usual effective dose range
  • Dosage adjustments based on clinical response & tolerability
  • Recommended dosage for different conditions

Interaction

  • Caution with medicines causing electrolyte imbalance
  • Co-administration effects with other drugs

Contraindications

  • Contra-indicated in patients hypersensitive to the drug

Side Effects

  • Most commonly reported Adverse Drug Reactions (ADRs)
  • Includes somnolence, dizziness, dry mouth, weight gain

Pregnancy & Lactation

  • Safety and efficacy during human pregnancy not established
  • Benefits vs potential risks during pregnancy
  • Unknown excretion into human milk
  • Advice for breastfeeding women

Precautions & Warnings

  • Risk of suicidal thoughts and self-harm
  • Caution in patients with cardiovascular disease
  • Orthostatic hypotension risk
  • Caution in treating patients with a history of seizures
  • Consideration of dose reduction for tardive dyskinesia
  • Concerns about neuroleptic malignant syndrome
  • Caution in patients with cardiovascular disease or family history of QT prolongation
  • Reported cases of severe neutropenia
  • Observations of increases in blood glucose and hyperglycaemia

Use in Special Populations

  • Caution in the elderly
  • Therapeutic dose adjustments for elderly
  • Inappropriateness for children and adolescents below 18 years

Overdose Effects

  • Reported survival in acute overdoses
  • No specific antidote
  • Recommendations for intensive care procedures
  • Treatment for refractory hypotension in case of overdose

Therapeutic Class

  • Belongs to atypical neuroleptic drugs

Storage Conditions

  • Keep out of the reach of children
  • Expiry date and storage instructions
  • Storage in a cool, dry place away from light

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