Quiet 25 mg (Tablet)
Unit Price: ৳ 3.00 (5 x 10: ৳ 150.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Quetiapine fumarate |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of acute and chronic psychoses
- Treatment of schizophrenia
- Treatment of bipolar disorder
- Maintenance treatment of bipolar I disorder
- Combination therapy with a mood stabilizer
- Prevention of recurrence of manic, depressive, or mixed episodes
Pharmacology
- Belongs to dibenzothiazepine derivatives
- Antagonist at multiple neurotransmitter receptors in the brain
- Targets serotonin, dopamine, histamine, and adrenergic receptors
- Mechanism of action is unknown
- Proposed efficacy in schizophrenia through dopamine and serotonin antagonism
- Antagonism of histamine receptors may cause somnolence
Dosage & Administration
- Administered twice daily
- Total daily dose for the first four days
- Titration to the usual effective dose range
- Further dosage adjustments for different conditions
- Usual effective dose range
- Adjusted based on clinical response and tolerability
- Administered once daily at bedtime
- Usual dose for depressive episodes
- Combination therapy dosage
- Women's advised action during breastfeeding
Interaction
- Caution with medicines causing electrolyte imbalance
- Co-administration effects with thioridazine, carbamazepine, and phenytoin
Contraindications
- Contra-indicated in patients hypersensitive to it
Side Effects
- Commonly reported adverse drug reactions
- List of common adverse effects
Pregnancy & Lactation
- Safety and efficacy during human pregnancy not established
- Use during pregnancy should justify potential risks
- Excretion into human milk is unknown
- Women advised to avoid breastfeeding while taking Quetiapine
Precautions & Warnings
- Association of depression with increased risk of suicidal thoughts and self-harm
- Caution in patients with known cardiovascular disease or conditions predisposing to hypotension
- Caution when treating patients with a history of seizures
- Consideration for dose reduction or discontinuation
- Association with neuroleptic malignant syndrome
- Caution with cardiovascular disease or family history of QT prolongation
- Reported cases of severe neutropenia and hyperglycemia
- Use with caution in the elderly
- Not indicated for use in children and adolescents below 18 years of age
Use in Special Populations
- Caution in the elderly
- Slower rate of dose titration and lower daily therapeutic dose
- Not indicated for children and adolescents below 18 years of age
Overdose Effects
- Reported survival in acute overdoses
- No specific antidote
- Consideration of multiple drug involvement
- Recommended intensive care procedures
- Treatment for refractory hypotension
Therapeutic Class
- Belongs to atypical neuroleptic drugs
Storage Conditions
- Keep out of the sight and reach of children
- Do not use after the expiry date
- Store in a cool and dry place away from light