Quiet 100 mg (Tablet)
Unit Price: ৳ 10.00 (5 x 10: ৳ 500.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Quetiapine fumarate |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Title
- Quiet Antipsychotic Medication
Categories
- Medicine
- Healthcare
- Pharmaceutical
Description
- Quetiapine Fumarate is an atypical psychotropic agent used for the treatment of acute and chronic psychoses, including schizophrenia, bipolar disorder, and manic episodes. The medication has pharmacological properties as an antagonist at multiple neurotransmitter receptors in the brain, exhibits various dosage and administration regimens for different conditions, and presents specific precautions and warnings for use in special populations.
Indications
- Treatment of acute and chronic psychoses
- Treatment of schizophrenia
- Treatment of manic episodes associated with bipolar disorder
- Treatment of depressive episodes associated with bipolar disorder
- Maintenance treatment of bipolar I disorder in combination with a mood stabilizer
- Prevention of recurrence of manic, depressive or mixed episodes
Mode of Action
- Atypical psychotropic agent
- Antagonist at serotonin and dopamine receptors
- No appreciable affinity at cholinergic muscarinic and benzodiazepine receptors
- Mechanism of action unknown
Dosage and Administration
- Twice daily administration
- Administration with or without food
- Initial titration dosage for the first four days
- Usual effective dose range
- Dosage adjustments based on clinical response and tolerability
- Different dosing regimens for different indications
Interaction
- Caution with medicines causing electrolyte imbalance or QT interval prolongation
- Co-administration effects with thioridazine, carbamazepine, and phenytoin
Contraindications
- Hypersensitivity to quetiapine
Side Effects
- Somnolence
- Dizziness
- Dry mouth
- Withdrawal symptoms
- Elevations in serum triglyceride levels
- Elevations in total cholesterol
- Decreases in HDL cholesterol
- Weight gain
- Decreased hemoglobin
- Extrapyramidal symptoms
Pregnancy and Lactation
- Safety and efficacy in pregnancy not established
- Use only if benefits outweigh potential risks
- Advice against breastfeeding while taking quetiapine
Precautions and Warnings
- Risk of suicidal thoughts and self-harm
- Caution in patients with known cardiovascular disease or predisposing conditions
- Risk of orthostatic hypotension
- Caution in patients with history of seizures
- Consideration of dose reduction in tardive dyskinesia
- Caution in patients with family history of QT prolongation
- Risk of neutropenia, hyperglycemia, and diabetes mellitus
Use in Special Populations
- Caution in the elderly
- Dose adjustment for elderly and slower titration
- Not indicated for use in children and adolescents below 18 years
Overdose Effects
- Survival reported in acute overdoses
- No specific antidote
- Consideration of multiple drug involvement
- Intensive care procedures recommended
- Treatment of refractory hypotension
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Keep out of reach of children
- Do not use after expiry date
- Store in a cool and dry place away from light