Qutipin 25 mg (Tablet)

Unit Price: ৳ 3.01 (10 x 10: ৳ 301.00)
Strip Price: ৳ 30.10

Medicine Details

Indications

  • Treatment of Acute and chronic psychoses
  • Treatment of schizophrenia
  • Treatment of Bipolar Disorder
  • Treatment of manic episodes
  • Treatment of depressive episodes
  • Maintenance treatment of bipolar I disorder
  • Prevention of recurrence of manic, depressive or mixed episodes

Pharmacology

  • Atypical psychotropic agent
  • Dibenzothiazepine derivatives
  • Antagonist at neurotransmitter receptors
  • Serotonin 5HT1A and 5HT2 receptors
  • Dopamine D1 and D2 receptors
  • Histamine H1 receptor antagonist
  • Adrenergic alpha1 and alpha2 receptor antagonist

Dosage & Administration

  • Administered twice daily
  • Administered with or without food
  • Initial dose titration for the first four days
  • Usual effective dose range
  • Titration to the usual effective dose range
  • Further dosage adjustments
  • Usual effective dose

Interaction

  • Medicines known to cause electrolyte imbalance
  • Medicines known to increase QT interval
  • Co-administration with thioridazine
  • Co-administration with carbamazepine
  • Co-administration with phenytoin

Contraindications

  • Hypersensitivity to Quetiapine

Side Effects

  • Somnolence
  • Dizziness
  • Dry mouth
  • Withdrawal symptoms
  • Elevations in serum triglyceride levels
  • Elevations in total cholesterol
  • Decreases in HDL cholesterol
  • Weight gain
  • Decreased haemoglobin
  • Extrapyramidal symptoms

Pregnancy & Lactation

  • Safety and efficacy during human pregnancy not established
  • Use during pregnancy if benefits justify potential risks
  • Lowest possible dose and duration of treatment during pregnancy
  • Excretion into human milk is unknown
  • Avoid breastfeeding while taking Quetiapine

Precautions & Warnings

  • Suicidal thoughts or clinical worsening
  • Use with caution in patients with known cardiovascular disease
  • Use with caution in patients with cerebrovascular disease
  • Use with caution in patients predisposing to hypotension
  • Caution when treating patients with a history of seizures
  • Consider dose reduction or discontinuation if tardive dyskinesia appears
  • Discontinue and provide appropriate medical treatment for Neuroleptic Malignant Syndrome
  • Exercise caution in patients with cardiovascular disease or family history of QT prolongation
  • Rare reports of severe neutropenia
  • Observation of blood glucose levels and occasional reports of diabetes
  • Use with caution in the elderly
  • Not indicated for use in children and adolescents below 18 years of age

Use in Special Populations

  • Use with caution in the elderly
  • Slower rate of dose titration and lower daily therapeutic dose in the elderly
  • Not indicated for use in children and adolescents below 18 years of age

Overdose Effects

  • Survival reported in acute overdoses
  • No specific antidote
  • Consider multiple drug involvement in severe intoxication
  • Intensive care procedures recommended
  • Treatment of refractory hypotension with appropriate measures
  • Close medical supervision and monitoring

Therapeutic Class

  • Atypical neuroleptic drugs

Storage Conditions

  • Keep out of the sight and reach of children
  • Do not use after the expiry date
  • Store in a cool and dry place away from light

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