Qmax 100 mg (Tablet)
Unit Price: ৳ 10.03 (5 x 10: ৳ 501.50)
Strip Price: ৳ 100.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Quetiapine fumarate |
| Company | Aci limited |
| Also available as |
Indications
- Treatment of acute and chronic psychoses
- Treatment of schizophrenia
- Treatment of bipolar disorder including manic episodes and depressive episodes
- Maintenance treatment of bipolar I disorder
Pharmacology
- Belongs to dibenzothiazepine derivatives
- Antagonist at multiple neurotransmitter receptors
- No appreciable affinity at cholinergic muscarinic and benzodiazepine receptors
- Mechanism of action is unknown
- Efficacy in schizophrenia is mediated through dopamine D2 and serotonin 5HT2 antagonism
Dosage & Administration
- Administered twice daily
- Total daily dose for the first four days of therapy
- Dosage adjustments based on clinical response and tolerability
- Usual effective dose range
- Administered once daily at bedtime for depressive episodes associated with bipolar disorder
Interaction
- Caution with medicines causing electrolyte imbalance or increasing QT interval
- Co-administration with thioridazine, carbamazepine, phenytoin increased Qmax clearance
Contraindications
- Hypersensitivity to Quetiapine
Side Effects
- Somnolence
- Dizziness
- Dry mouth
- Elevations in serum triglyceride levels
- Weight gain
- Decreased haemoglobin
- Extrapyramidal symptoms
Pregnancy & Lactation
- Safety and efficacy not established during human pregnancy
- Potential risks during pregnancy
- Breastfeeding while taking Quetiapine should be avoided
Precautions & Warnings
- Increased risk of suicidal thoughts and self-harm
- Caution in patients with cardiovascular or cerebrovascular disease
- Caution in patients with a history of seizures
- Consideration of dose reduction or discontinuation if tardive dyskinesia appears
- Discontinuation and medical treatment for neuroleptic malignant syndrome
- Caution in patients with cardiovascular disease or family history of QT prolongation
- Monitoring for severe neutropenia and hyperglycemia
- Elderly use with caution
- Not indicated for use in children and adolescents below 18 years of age
Use in Special Populations
- Use with caution in the elderly
- Not indicated for use in children and adolescents below 18 years of age
Overdose Effects
- Survival reported in acute overdoses
- No specific antidote
- Consider multiple drug involvement
- Intensive care procedures recommended
- Treatment of refractory hypotension with appropriate measures
- Close medical supervision and monitoring
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Keep out of the reach of children
- Do not use after expiry date
- Store in a cool and dry place away from light