Risdon 1 mg (Tablet)
Unit Price: ৳ 3.00 (3 x 10: ৳ 90.00)
Strip Price: ৳ 30.00
Medicine Details
Category | Details |
---|---|
Generic | Risperidone oral |
Company | Unimed unihealth pharmaceuticals ltd |
Also available as |
Indications
- Treatment of acute and chronic psychoses
- Treatment of mania
- Treatment of schizophrenia
Pharmacology
- Selective monoaminergic antagonist
- High affinity for serotoninergic 5-HT2 and dopaminergic D2 receptors
- Binds also to alpha1 adrenergic receptors
- Binds with lower affinity to H1 histamine and alpha2 adrenergic receptors
- No affinity for cholinergic receptors
- Reduces extrapyramidal side effect liability
- Improves positive symptoms of schizophrenia
- Balanced central serotonin and dopamine antagonism
Dosage & Administration
- Initial dose of 2 mg in 1-2 divided doses on the first day
- Usual dose range of 4-6 mg daily
- Max dose of 16 mg daily
- Lower initial dose for elderly patients or those with hepatic or renal impairment
- Initial dose of 1 mg daily for elderly patients or those with hepatic or renal impairment
- Dose adjustments for mania treatment
- Dose adjustments for schizophrenia treatment
- Dose adjustments at intervals of not less than 1 week
- Small dose increments/decrements of 1-2 mg recommended for dosage adjustments
Interaction
- Antagonizes the effects of levodopa and dopamine agonists
- Reduces plasma clearance with chronic administration of Carbamazepine
- May decrease the clearance with chronic administration of Clozapine
- Enhances the effects of certain antihypertensives
Contraindications
- Hypersensitivity to the product
Side Effects
- Insomnia
- Agitation
- Anxiety
- Headache
- Drowsiness
- Impaired concentration
- Fatigue
- Blurred vision
- Constipation
- Nausea and vomiting
- Dyspepsia
- Abdominal pain
- Hyperprolactinaemia
- Urine incontinence
- Tachycardia
- Hypertension
- Edema
- Rash
- Rhinitis
- Cerebrovascular accident
- Neurtropenia
- Thrombocytopenia
Pregnancy & Lactation
- No direct reproductive toxicity in experimental animals
- Indirect prolactin- and CNS-mediated effects observed
- No teratogenic effect noted
- Safety for use during human pregnancy not established
- Excreted in milk
- Should not breastfeed while receiving
Precautions & Warnings
- Precaution for preexisting cardiovascular diseases
- Discontinue use if signs and symptoms of tardive dyskinesia occur
- Precaution for renal and hepatic impairment
- Precaution for elderly, epilepsy, and Parkinson's disease
- Precaution in pregnancy
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children