Risperdex 2 mg (Tablet)
Unit Price: ৳ 3.00 (5 x 10: ৳ 150.00)
Strip Price: ৳ 30.00
Medicine Details
Category | Details |
---|---|
Generic | Risperidone oral |
Company | Opsonin pharma ltd |
Also available as |
Indications
- Acute and chronic psychoses
- Mania
- Schizophrenia
Pharmacology
- Selective monoaminergic antagonist
- High affinity for serotoninergic 5-HT2 and dopaminergic D2 receptors
- Binds to alpha1 adrenergic receptors
- Low affinity for H1 histamine and alpha2 adrenergic receptors
- No affinity for cholinergic receptors
- Improves positive symptoms of schizophrenia
- Balanced central serotonin and dopamine antagonism
Dosage & Administration
- Initial dose of 2 mg in 1-2 divided doses
- Usual dose range 4-6 mg daily for psychoses
- Adjustments for elderly or hepatic/renal impairment
- Initial dose of 2 mg once daily for mania
- Usual dose range 1-6 mg daily for mania
- Initial dose of 1 mg BID for schizophrenia
- Target dose of 3 mg BID for schizophrenia
- Dosage adjustments at intervals of not less than 1 week
Interactions
- May antagonize the effects of levodopa and dopamine agonists
- Reduction in plasma clearance with Carbamazepine
- Decrease in clearance with Clozapine
- Enhancement of effects of certain antihypertensives
Contraindications
- Known hypersensitivity to the product
Side Effects
- Insomnia
- Agitation
- Anxiety
- Headache
- Drowsiness
- Impaired concentration
- Fatigue
- Blurred vision
- Constipation
- Nausea and vomiting
- Dyspepsia
- Abdominal pain
- Hyperprolactinaemia
- Urine incontinence
- Tachycardia
- Hypertension
- Edema
- Rash
- Rhinitis
- Cerebrovascular accident
- Neurtropenia
- Thrombocytopenia
Pregnancy & Lactation
- No direct reproductive toxicity in experimental animals
- No teratogenicity effect noted
- Safety for use during human pregnancy not established
- Excreted in milk
- Should not breastfeed
Precautions & Warnings
- Preexisting cardiovascular diseases
- Tardive dyskinesia
- Renal and hepatic impairment
- Elderly epilepsy
- Parkinson's disease
- Pregnancy
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children