Rispolux 4 mg (Tablet)

Unit Price: ৳ 9.50 (3 x 10: ৳ 285.00)
Strip Price: ৳ 95.00

Medicine Details

Indications

  • Acute and chronic psychoses
  • Mania
  • Schizophrenia

Pharmacology

  • Selective monoaminergic antagonist
  • High affinity for serotoninergic 5-HT2 and dopaminergic D2 receptors
  • Binds to alpha1 adrenergic receptors
  • Lower affinity to H1 histamine and alpha2 adrenergic receptors
  • No affinity for cholinergic receptors
  • Balanced central serotonin and dopamine antagonism

Dosage & Administration

  • Initial dose of 2 mg in 1-2 divided doses
  • Usual dose range of 4-6 mg daily
  • Max dosage of 16 mg daily
  • Special dosage for elderly or hepatic/renal impairment
  • Not recommended for children under 15 years
  • Specific dosages for mania and schizophrenia

Interaction

  • Antagonizes effects of levodopa and dopamine agonists
  • Reduces plasma clearance with chronic Carbamazepine administration
  • Decreases clearance with chronic Clozapine administration
  • Enhances effects of certain antihypertensives

Contraindications

  • Known hypersensitivity to the product

Side Effects

  • Insomnia
  • Agitation
  • Anxiety
  • Headache
  • Drowsiness
  • Impaired concentration
  • Fatigue
  • Blurred vision
  • Constipation
  • Nausea and vomiting
  • Dyspepsia
  • Abdominal pain
  • Hyperprolactinaemia
  • Urinary incontinence
  • Tachycardia
  • Hypertension
  • Edema
  • Rash
  • Rhinitis
  • Cerebrovascular accident
  • Neurtropenia
  • Thrombocytopenia

Pregnancy & Lactation

  • No established safety in human pregnancy
  • Excreted in breast milk

Precautions & Warnings

  • Special precaution for preexisting cardiovascular diseases
  • Discontinue use if signs of tardive dyskinesia occur
  • Contraindicated in renal and hepatic impairment, elderly epilepsy, Parkinson's disease
  • Not recommended during pregnancy

Therapeutic Class

  • Atypical neuroleptic drugs

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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