Sizodon 1 mg (Tablet)

Unit Price: ৳ 3.01 (10 x 10: ৳ 301.00)
Strip Price: ৳ 30.10

Medicine Details

Indications

  • Acute and chronic psychoses
  • Mania
  • Schizophrenia

Pharmacology

  • Selective monoaminergic antagonist
  • High affinity for serotoninergic 5-HT2 and dopaminergic D2 receptors
  • Binds to alpha1 adrenergic receptors
  • No affinity for 8 cholinergic receptors
  • Balanced central serotonin and dopamine antagonism

Dosage & Administration

  • Usual dose range 4-6 mg daily for psychoses
  • Usual dose range 1-6 mg daily for mania
  • Target dose of 3 mg BID for schizophrenia

Interaction

  • Antagonizes effects of levodopa and dopamine agonists
  • Reduces plasma clearance with chronic administration of Carbamazepine
  • Enhances effects of certain antihypertensives

Contraindications

  • Known hypersensitivity to the product

Side Effects

  • Insomnia
  • Agitation
  • Anxiety
  • Headache
  • Drowsiness
  • Impaired concentration
  • Fatigue
  • Blurred vision
  • Constipation
  • Nausea and vomiting
  • Dyspepsia
  • Abdominal pain
  • Hyperprolactinaemia
  • Urine incontinence
  • Tachycardia
  • Hypertension
  • Edema
  • Rash
  • Rhinitis
  • Cerebrovascular accident
  • Neutropenia
  • Thrombocytopenia

Pregnancy & Lactation

  • No direct reproductive toxicity observed in experimental animals
  • No teratogenicity effect noted in any study
  • Safety for use during human pregnancy not established
  • Risperidone and 9-hydroxyrisperidone excreted in breast milk
  • Women receiving Risperidone should not breastfeed

Precautions & Warnings

  • Special precaution in preexisting cardiovascular diseases
  • Discontinue use if signs of tardive dyskinesia occur
  • Special precaution for renal and hepatic impairment, elderly, epilepsy, Parkinson's disease, and pregnancy

Therapeutic Class

  • Atypical neuroleptic drugs

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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