Sizodon 4 mg (Tablet)

Unit Price: ৳ 9.03 (5 x 10: ৳ 451.50)
Strip Price: ৳ 90.30

Medicine Details

Category Details
Generic Risperidone oral
Company Sun pharmaceutical bangladesh ltd
Also available as
Sizodon 1 mg tablet Sizodon 2 mg tablet Sizodon md 1 mg tablet Sizodon md 2 mg tablet Sizodon md 4 mg tablet

Title

  • Sizodon Tablet

Categories

  • Medicine
  • Pharmaceuticals
  • Neuroleptic Drugs

Description

  • Indications:
    • Acute and chronic psychoses
    • Mania
    • Schizophrenia
  • Pharmacology: Risperidone is a selective monoaminergic antagonist having high affinity for serotoninergic 5-HT2 and dopaminergic D2 receptors. Risperidone binds also to alpha1 adrenergic receptors and with lower affinity to H1 histamine and alpha2 adrenergic receptors. Risperidone has no affinity for cholinergic receptors. Risperidone, as a potent D2 antagonist, improves the positive symptoms of schizophrenia but causes less depression of motor activity. Balanced central serotonin and dopamine antagonism may reduce extrapyramidal side effect liability and extend the therapeutic activity to the negative and affective symptoms of schizophrenia.
  • Dosage & Administration:
    • Psychoses:
      • 2 mg in 1-2 divided doses on 1st day then 4 mg in 1-2 divided doses on second day
    • Mania:
      • Initially, 2 mg once daily increased if necessary in step of 1 mg daily
    • Schizophrenia:
      • Risperidone should be generally administered at 1 mg BID initially, with increases in increments of 1 mg BID on the second and third day, as tolerated, to a target dose of 3 mg BID by the third day
  • Interaction:
    • May antagonize the effects of levodopa and dopamine agonists
    • Chronic administration with Carbamazepine reduces plasma clearance of Sizodon
    • Chronic administration with Clozapine may decrease the clearance of Sizodon
    • May enhance the effects of certain antihypertensives
  • Contraindications:
    • Risperidone is contraindicated in patients with a known hypersensitivity to the product
  • Side Effects:
    • Insomnia
    • Agitation
    • Anxiety
    • Headache
    • Drowsiness
    • Impaired concentration
    • Fatigue
    • Blurred vision
    • Constipation
    • Nausea and vomiting
    • Dyspepsia
    • Abdominal pain
    • Hyperprolactinaemia
    • Urine incontinence
    • Tachycardia
    • Hypertension
    • Edema
    • Rash
    • Rhinitis
    • Cerebrovascular accident
    • Neutropenia
    • Thrombocytopenia
  • Pregnancy & Lactation:
    • Risperidone and 9-hydroxyrisperidone are excreted in human breast milk. Therefore, women receiving Risperidone should not breastfeed
  • Precautions & Warnings:
    • Special precaution should be taken in case of preexisting cardiovascular diseases
    • Discontinue use if signs and symptoms of tardive dyskinesia occur
    • Renal and hepatic impairment
    • Elderly epilepsy
    • Parkinson's disease
    • Pregnancy
  • Therapeutic Class:
    • Atypical neuroleptic drugs
  • Storage Conditions:
    • Do not store above 30°C
    • Keep away from light and out of the reach of children

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