Sperid 1 mg (Tablet)
Unit Price: ৳ 3.00 (5 x 10: ৳ 150.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Risperidone oral |
| Company | Renata limited |
| Also available as |
Title
- Sperid Tablet
Categories
- Medicine
- Pharmaceutical
Description
- Sperid tablet is indicated for the treatment of acute and chronic psychoses, mania, and schizophrenia. It contains risperidone, a selective monoaminergic antagonist with high affinity for serotoninergic 5-HT2 and dopaminergic D2 receptors.
Indications
- Acute and chronic psychoses
- Mania
- Schizophrenia
Pharmacology
- Selective monoaminergic antagonist
- High affinity for serotoninergic 5-HT2 and dopaminergic D2 receptors
- Binds to alpha1 adrenergic receptors
- Binds with lower affinity to H1 histamine and alpha2 adrenergic receptors
- No affinity for cholinergic receptors
- Improves positive symptoms of schizophrenia
- Balanced central serotonin and dopamine antagonism
- Reduces extrapyramidal side effect liability
Dosage & Administration
- 2 mg in 1-2 divided doses on 1st day, then 4 mg on the second day
- Usual dose range 4-6 mg daily
- Max dosage 16 mg daily
- Initial dosage for elderly or in hepatic or renal impairment: 1 mg daily in two divided doses increased in steps
- Usual dose range for mania: 1-6 mg daily
- Initial dosage for mania in elderly or in hepatic or renal impairment: 1 mg daily in two divided doses increased in steps
- Risperidone should be generally administered at 1 mg BID initially for schizophrenia
Interaction
- May antagonize the effects of levodopa and dopamine agonists
- Chronic administration with carbamazepine reduces plasma clearance
- Chronic administration with clozapine may decrease the clearance
- May enhance the effects of certain antihypertensives
Contraindications
- Known hypersensitivity to the product
Side Effects
- Insomnia
- Agitation
- Anxiety
- Headache
- Drowsiness
- Impaired concentration
- Fatigue
- Blurred vision
- Constipation
- Nausea and vomiting
- Dyspepsia
- Abdominal pain
- Hyperprolactinaemia
- Urine incontinence
- Tachycardia
- Hypertension
- Edema
- Rash
- Rhinitis
- Cerebrovascular accident
- Neutropenia
- Thrombocytopenia
Pregnancy & Lactation
- No established safety for use during human pregnancy
- Risperidone and 9-hydroxyrisperidone are excreted in human breast milk
Precautions & Warnings
- Preexisting cardiovascular diseases
- Tardive dyskinesia
- Renal and hepatic impairment
- Elderly epilepsy
- Parkinson's disease
- Pregnancy
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children