Timex 25 mg (Tablet)

Unit Price: ৳ 9.00 (5 x 10: ৳ 450.00)
Strip Price: ৳ 90.00

Medicine Details

Category Details
Generic Clomipramine hydrochloride
Company Orion pharma ltd

Indications

  • Obsessive Compulsive Disorder (OCD)
  • Major Depressive Disorder (MDD)
  • Depression

Pharmacology

  • Tricyclic antidepressant
  • Influences obsessive and compulsive behaviors
  • Affects serotonergic neuronal transmission
  • Inhibits reuptake of serotonin (5-HT)

Dosage

  • Initial dose: 25 mg at bedtime
  • Max adult dose: 150 mg per day
  • Max elderly patient dose: 75 mg per day
  • Divided dose for reducing gastrointestinal disturbances
  • Not recommended for children

Administration

  • Swallow capsules whole with water
  • Continue treatment until advised by doctor
  • May take up to 4 weeks to work
  • Can be taken as one dose at night or as smaller doses at intervals during the day

Interaction

  • Interacts with various medicines for depression
  • Interacts with MAOIs, SSRIs, SNaRIs, tricyclic and tetracyclic antidepressants, diuretics, anaesthetics, blood pressure lowering agents, and anti-coagulants

Contraindications

  • Hypersensitivity to Clomipramine Hydrochloride or other tricyclic antidepressants
  • Acute recovery phase following a myocardial infarction
  • Not to be used with MAO inhibitors within 14 days

Side Effects

  • Gastrointestinal disturbances
  • Headache
  • Dizziness
  • Nausea
  • Constipation
  • Dry mouth
  • Increased sweating
  • Shaking hands
  • Tremor
  • Difficulty in passing urine
  • Eye problems
  • Fatigue or drowsiness
  • Sexual disturbances
  • Restlessness

Pregnancy & Lactation

  • Limited data on safety for pregnancy
  • Likely excreted in human breast milk
  • Known risk of fetal damage

Precautions & Warnings

  • Consult doctor or pharmacist before use
  • Prior history of suicidal thoughts
  • History of epilepsy or fits
  • Head injury or brain damage
  • Undergoing electric shock therapy (ECT)
  • Heart problems
  • Low potassium level in blood (hypokalaemia)
  • Kidney disease
  • Schizophrenia or other mental health conditions
  • Blood disorder
  • Overactive thyroid gland
  • Severe long-term constipation
  • Tumor of the adrenal gland
  • Liver disease
  • Low blood pressure
  • Use of contact lenses

Overdose Effects

  • Dry mouth
  • Dilated pupils
  • Coma
  • Convulsions
  • Tachycardia/cardiac arrhythmia
  • Respiratory depression
  • Alterations in blood pressure

Therapeutic Class

  • Tricyclic & related antidepressant drugs

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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