Citalex 10 mg (Tablet)

Unit Price: ৳ 9.00 (2 x 10: ৳ 180.00)

Strip Price: ৳ 90.00

Medicine Details

Escitalopram is an orally administered selective serotonin reuptake inhibitor (SSRI)
Escitalopram is the pure S-enantiomer of the racemic bicyclic phthalate derivative citalopram
At least 100 fold more potent than the R-enantiomer with respect to inhibition of 5-HT reuptake
No or very low affinity for serotonergic or other receptors including alpha- and beta-adrenergic Dopamine, Histamine, Muscarinic and benzodiazepine receptors

Safety of daily doses above 20 mg has not been demonstrated
Admiistered as a single daily dose
Usual dosage for major depressive episodes is 10 mg once daily
Initial dosage for panic disorder with or without agoraphobia is 5 mg once daily
Usual dosage for social anxiety disorder is 10 mg once daily
Initial dosage for obsessive-compulsive disorder is 10 mg once daily

SSRI or related antidepressants should not be started until 2 weeks after stopping an MAOI
An MAOI should not be started until at least a week after an SSRI or related antidepressant has been stopped

Contraindicated in patients with known hypersensitivity to Escitalopram or Citalopram or any of the inactive ingredients of the drug product
Concomitant use of escitalopram in patients taking monoamine oxidase/pimozide iscontraindicated

Less sedating and have fewer antimuscarinic and cardiotoxic effects than tricyclic antidepressants
Common side-effects include nausea, vomiting, dyspepsia, abdominal pain, diarrhoea, constipation
Other side-effects include dry mouth, nervousness, anxiety, headache, insomnia, tremor, dizziness, asthenia, hallucinations, drowsiness, convulsions, galactorrhoea, sexual dysfunction, urinary retention, sweating, hypomania or mania, movement disorders and dyskinesias, visual disturbances

Physician should carefully consider the potential risks and benfits of treatment when treating a pregnant woman with Escitalopram during the third trimester
Excreted in human breast milk

Use with caution in patients with epilepsy, cardiac disease, diabetes mellitus, angle-closure glaucoma, hepatic and renal impairment
Avoid if poorly controlled epilepsy or if convulsions develop
Prolonged seizures reported with fluoxetine

Elderly patients (>65 years of age) should start with 5 mg once daily
Not recommended for children and adolescents (<18 years of age)
Dosage adjustment not necessary in patients with mild or moderate renal impairment
Initial dose of 5 mg daily for the first two weeks of treatment recommended in patients with mild or moderate hepatic impairment

Symptoms include dizziness, tremor, agitation, serotonin syndrome, convulsion, coma, nausea, vomiting, hypotension, tachycardia, QT interval prolongation, arrhythmia, hypokalaemia, hyponatremia
No specific antidote
Gastric lavage and activated charcoal may be considered
ECG monitoring advised in case of overdose