Citalon 10 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Escitalopram oxalate |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of major depressive episodes
- Treatment of panic disorder with or without agoraphobia
- Treatment of social anxiety disorder (social phobia)
- Treatment of generalised anxiety disorder
- Treatment of obsessive-compulsive disorder
Pharmacology
- Selective serotonin reuptake inhibitor (SSRI)
- Pure S-enantiomer of the racemic bicyclic phthalate derivative citalopram
- 100 fold more potent than the R-enantiomer with respect to inhibition of 5-HT reuptake
Dosage
- Usual dosage of 10 mg once daily for major depressive episodes
- Initial dose of 5 mg for panic disorder with or without agoraphobia
- Usual dosage of 10 mg once daily for social anxiety disorder
- Initial dosage of 10 mg once daily for generalised anxiety disorder
- Initial dosage of 10 mg once daily for obsessive-compulsive disorder
Administration
Generally administered once daily, morning or evening with or without food
Interaction
SSRI or related antidepressants should not be started until 2 weeks after stopping an MAOI. Conversely, an MAOI should not be started until at least a week after an SSRI or related antidepressant has been stopped
Contraindications
Contraindicated in patients with known hypersensitivity to Escitalopram or Citalopram or any of the inactive ingredients of the drug product. Concomitant use of escitalopram in patients taking monoamine oxidase/pimozide is contraindicated
Side Effects
- Less sedating and have fewer antimuscarinic and cardiotoxic effects than tricyclic antidepressants
- Common side-effects include gastrointestinal effects, anorexia with weight loss, hypersensitivity reactions, dry mouth, nervousness, anxiety, headache, insomnia, tremor, dizziness, asthenia, hallucinations, sexual dysfunction, movement disorders, visual disturbances
Pregnancy & Lactation
Excreted in human breast milk. The decision to continue or discontinue nursing should take into account the risk of citalopram exposure for the infant and the benefits of treatment for the mother
Precautions & Warnings
Should be used with caution in patients with epilepsy, concurrent electroconvulsive therapy, history of mania, cardiac disease, diabetes mellitus, angle-closure glaucoma, concomitant use of drugs that increase risk of bleeding, history of bleeding disorders, hepatic and renal impairment
Use in Special Populations
- Initial dosage of 5 mg once daily for elderly patients
- Not to be used in children and adolescents under the age of 18 years
- Dosage adjustment is not necessary in patients with mild or moderate renal impairment
- An initial dose of 5 mg daily for the first two weeks of treatment is recommended in patients with mild or moderate hepatic impairment
- For patients known to be poor metabolisers with respect to CYP2C19, an initial dose of 5 mg daily is recommended
Overdose Effects
- Symptoms mainly related to the central nervous system, gastrointestinal system, cardiovascular system, and electrolyte/fluid balance conditions
- No specific antidote
- General symptomatic supportive measures are recommended
Therapeutic Class
SSRIs & related antidepressant drugs
Storage Conditions
Store below 30°C temperature and protect from light & moisture. Keep the medicine out of the reach of children