Esita 10 mg (Tablet)

Unit Price: ৳ 12.00 (10 x 10: ৳ 1,200.00)

Strip Price: ৳ 120.00

Medicine Details

Category	Details
Generic	Escitalopram oxalate
Company	Healthcare pharmaceuticals ltd
Also available as	Esita 5 mg tablet

Escitalopram is an orally administered selective serotonin reuptake inhibitor (SSRI)
Escitalopram is the pure S-enantiomer of the racemic bicyclic phthalate derivative citalopram

Safety of daily doses above 20 mg has not been demonstrated
Usual dosage is 10 mg once daily for major depressive episodes
Initial dosage of 5 mg is recommended for panic disorder before increasing to 10 mg daily
Usual dosage is 10 mg once daily for social anxiety disorder
Initial dosage is 10 mg once daily for generalised anxiety disorder
Initial dosage is 10 mg once daily for obsessive-compulsive disorder

Escitalopram should generally be administered once daily, morning or evening with or without food

SSRI or related antidepressants should not be started until 2 weeks after stopping an MAOI
An MAOI should not be started until at least a week after an SSRI or related antidepressant has been stopped

Escitalopram is contraindicated in patients with known hypersensitivity to Escitalopram or Citalopram or any of the inactive ingredients of the drug product
Concomitant use of escitalopram in patients taking monoamine oxidase/pimozide is contraindicated

SSRIs are less sedating and have fewer antimuscarinic and cardiotoxic effects than tricyclic antidepressants
Side-effects of the SSRIs include gastrointestinal effects, anorexia with weight loss or increased appetite and weight gain, hypersensitivity reactions, dry mouth, nervousness, anxiety, headache, insomnia, tremor, dizziness, asthenia, hallucinations, drowsiness, convulsions, galactorrhoea, sexual dysfunction, urinary retention, sweating, hypomania or mania, movement disorders and dyskinesias, visual disturbances

Consider the potential risks and benefits of treatment when treating a pregnant woman with Escitalopram during the third trimester
Escitalopram is excreted in human breast milk, decision whether to continue or discontinue nursing should take into account the risk of citalopram exposure for the infant and the benefits Escitalopram treatment for the mother

SSRIs should be used with caution in patients with epilepsy, concurrent electroconvulsive therapy, history of mania, cardiac disease, diabetes mellitus, angle-closure glaucoma, concomitant use of drugs that increase risk of bleeding, history of bleeding disorders, hepatic and renal impairment

Initial dosage for elderly patients (>65 years of age) is 5 mg once daily
Do not use Esita in the treatment of children and adolescents under the age of 18 years
Dosage adjustment is not necessary in patients with mild or moderate renal impairment
Dosage adjustment is recommended for patients with mild or moderate hepatic impairment
Initial dosage of 5 mg daily is recommended for patients who are known to be poor metabolisers with respect to CYP2C19
Gradually reduce the dose over a period of at least one to two weeks to reduce the risk of discontinuation symptoms when stopping treatment with escitalopram

Symptoms seen in a reported overdose of escitalopram include symptoms mainly related to the central nervous system, the gastrointestinal system, and the cardiovascular system, and electrolyte/fluid balance conditions
There is no specific antidote for escitalopram overdose, establish and maintain an airway, ensure adequate oxygenation and respiratory function, consider gastric lavage and the use of activated charcoal, cardiac and vital signs monitoring are recommended along with general symptomatic supportive measures, ECG monitoring is advised in case of overdose