Oxapro 5 mg (Tablet)
Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Escitalopram oxalate |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Treatment of major depressive episodes
- Treatment of panic disorder with or without agoraphobia
- Treatment of social anxiety disorder (social phobia)
- Treatment of generalised anxiety disorder
- Treatment of obsessive-compulsive disorder
Pharmacology
- Orally administered
- Selective serotonin reuptake inhibitor (SSRI)
- Pure S-enantiomer of the racemic bicyclic phthalate derivative citalopram
- At least 100 fold more potent than the R-enantiomer with respect to inhibition of 5-HT reuptake
- No or very low affinity for serotonergic or other receptors including alpha- and beta-adrenergic Dopamine, Histamine, Muscarinic and benzodiazepine receptors
Dosage
- Safety of daily doses above 20 mg not demonstrated
- Usually administered as a single daily dose
- May be taken with or without food
- Dose may be increased to a maximum of 20 mg daily depending on individual patient response
- Initial dosage for panic disorder with or without agoraphobia is 5 mg, may be increased to 10 mg daily
Administration
- Generally administered once daily
- Morning or evening with or without food
Interaction
- SSRI or related antidepressants should not be started until 2 weeks after stopping an MAOI
- An MAOI should not be started until at least a week after an SSRI or related antidepressant has been stopped
Contraindications
- Contraindicated in patients with known hypersensitivity to Escitalopram or Citalopram or any of the inactive ingredients of the drug product
- Concomitant use of escitalopram in patients taking monoamine oxidase/pimozide is contraindicated
Side Effects
- Gastrointestinal effects
- Anorexia with weight loss
- Increased appetite and weight gain
- Hypersensitivity reactions including rash, urticaria, angioedema
- Dry mouth
- Nervousness
- Anxiety
- Headache
- Insomnia
- Tremor
- Dizziness
- Asthenia
- Hallucinations
- Drowsiness
- Convulsions
Pregnancy & Lactation
- Physician should carefully consider the potential risks and benefits of treatment during the third trimester
- Excreted in human breast milk
Precautions & Warnings
- Use with caution in patients with epilepsy
- History of mania
- Cardiac disease
- Diabetes mellitus
- Angle-closure glaucoma
Use in Special Populations
- Elderly patients (>65 years of age)
- Children and adolescents (<18 years)
- Reduced renal function
- Reduced hepatic function
- Poor metabolizers of CYP2C19
Overdose Effects
- Symptoms mainly related to the central nervous system
- Serotonin syndrome
- Gastrointestinal symptoms
- Cardiovascular symptoms
- Electrolyte/fluid balance conditions
Therapeutic Class
- SSRIs & related anti-depressant drugs
Storage Conditions
- Store below 30°C temperature
- Protect from light & moisture