Citalam 10 mg (Tablet)

Unit Price: ৳ 12.00 (5 x 10: ৳ 600.00)

Strip Price: ৳ 120.00

Medicine Details

Orally administered selective serotonin reuptake inhibitor (SSRI)
Pure S-enantiomer of the racemic bicyclic phthalate derivative citalopram
At least 100 fold more potent than the R-enantiomer with respect to inhibition of 5-HT reuptake
No or very low affinity for serotonergic or other receptors including alpha- and beta-adrenergic Dopamine, Histamine, Muscarinic and benzodiazepine receptors

SSRI or related antidepressants should not be started until 2 weeks after stopping an MAOI
An MAOI should not be started until at least a week after an SSRI or related antidepressant has been stopped (2 weeks in the case of paroxetine and sertraline, at least 5 weeks in the case of fluoxetine)

Patients with known hypersensitivity to Escitalopram or Citalopram or any of the inactive ingredients of the drug product
Concomitant use of escitalopram in patients taking monoamine oxidase/pimozide is contraindicated

Less sedating and have fewer antimuscarinic and cardiotoxic effects than tricyclic antidepressants
Gastrointestinal effects include nausea, vomiting, dyspepsia, abdominal pain, diarrhoea, constipation
Anorexia with weight loss, increased appetite and weight gain reported
Hypersensitivity reactions including rash, urticaria, angioedema, anaphylaxis, arthralgia, myalgia, and photosensitivity
Other side-effects include dry mouth, nervousness, anxiety, headache, insomnia, tremor, dizziness, asthenia, hallucinations, drowsiness, convulsions, galactorrhoea, sexual dysfunction, urinary retention, sweating, hypomania or mania, movement disorders and dyskinesias, visual disturbances

Physician should carefully consider the potential risks and benefits of treatment when treating a pregnant woman with Escitalopram during the third trimester
Excreted in human breast milk, decision whether to continue or discontinue either nursing or Escitalopram therapy should take into account the risk of citalopram exposure for the infant and the benefits Escitalopram treatment for the mother

Use with caution in patients with epilepsy, history of mania, cardiac disease, diabetes mellitus, angle-closure glaucoma, concomitant use of drugs that increase risk of bleeding, history of bleeding disorders, hepatic and renal impairment

Elderly patients (>65 years of age) initial dosage is 5 mg once daily
Children and adolescents (<18 years) should not use Citalam
Dosage adjustment is not necessary in patients with mild or moderate renal impairment
Caution is advised in patients with severely reduced renal function (CLCR less than 30 ml/min)
An initial dose of 5 mg daily for the first two weeks of treatment is recommended in patients with mild or moderate hepatic impairment
For patients who are known to be poor metabolisers with respect to CYP2C19, an initial dose of 5 mg daily during the first two weeks of treatment is recommended

Symptoms mainly related to the central nervous system, gastrointestinal system, and the cardiovascular system
No specific antidote, establish and maintain an airway, ensure adequate oxygenation and respiratory function, gastric lavage and the use of activated charcoal should be considered, ECG monitoring is advised