Duloxen 30 mg (Tablet (Delayed Release))
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Duloxetine hydrochloride |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Major Depressive Disorder (MDD)
- Generalized Anxiety Disorder (GAD)
- Diabetic Peripheral Neuropathic Pain (DPNP)
- Fibromyalgia
- Chronic Musculoskeletal Pain
Pharmacology
Selective serotonin and norepinephrine reuptake inhibitor (SSNRI) for oral administration
Dosage & Administration
- Starting Dose: 30-60 mg/day
- Target Dose: 30-120 mg/day
- Maximum Dose: 120 mg/day
Metabolism Interaction
- Inhibited by CYP1A2 and CYP2D6 isozymes
- Co-administration with fluvoxamine increases AUC, Cmax and t
Contraindications
- Known hypersensitivity to drug or inactive ingredients
- Not approved for bipolar depression
- Patients with substantial alcohol use or chronic liver disease
- Cautious use in patients with controlled narrow-angle glaucoma
Side Effects
- Nausea
- Dizziness
- Dry mouth
- Constipation
- Decreased appetite
- Fatigue
- Somnolence
- Increased sweating
- Hyperhidrosis
- Asthenia
Pregnancy & Lactation
Pregnancy Category C: Should be used during pregnancy if benefit justifies the risk, not recommended during lactation
Precautions & Warnings
- Monitoring for clinical worsening and suicidality
- Blood pressure measurement prior to treatment and periodically thereafter
- Caution about risk of bleeding with concomitant use of Duloxen and NSAIDs or other coagulation-affecting drugs
- Prescribed with care in patients with a history of mania or seizure disorder
Use in Special Populations
Safety and efficacy in pediatric patients not established
Overdose Effects
Limited clinical experience; no specific antidote; general measures for overdose management
Therapeutic Class
Serotonin-norepinephrine reuptake inhibitor (SNRI)
Storage Conditions
Do not store above 30°C; Keep away from light and out of reach of children