Nodep 20 mg (Capsule)

Unit Price: ৳ 3.00 (5 x 10: ৳ 150.00)
Strip Price: ৳ 30.00

Medicine Details

Title and Categories

  • Nodep medicine
  • Phenothiazine related drugs
  • Antidepressant
  • Medication for depressive illness
  • Treatment for bulimia nervosa
  • Therapeutic drug for obsessive compulsive disorder

Dosage and Administration

  • Initial recommended dose of 20 mg/day
  • Maximum recommended dose of 80 mg/day
  • Maintenance dosage of 60 mg daily for bulimia nervosa
  • Lower dosage for patients with renal and/or hepatic impairment
  • Lower or less frequent dosage for elderly or patients with concurrent diseases
  • Not recommended for use in children

Interaction

  • Serious fatal reactions reported with MAO inhibitors
  • Greater than two-fold increase in stable plasma levels of other antidepressants
  • Reports of increased or decreased lithium levels when used concomitantly with Nodep
  • Elevation of blood levels of certain antipsychotics observed
  • Elevated plasma anticonvulsant concentrations and clinical anticonvulsant toxicity observed in some patients

Contraindications

  • Contraindicated in patients known to be hypersensitive to it
  • Not to be used in combination with MAOI or within 14 days of discontinuing therapy with MAOI
  • At least 5 weeks should be allowed after stopping Fluoxetine and before starting MAOI

Side Effects

  • Gastrointestinal: Nausea, vomiting, dyspepsia, dry mouth, diarrhea
  • Neurological: Anxiety, nervousness, insomnia/drowsiness, fatigue
  • Excessive sweating, pruritus, skin rashes associated with liver, kidney and lung involvement

Pregnancy & Lactation

  • Use in pregnancy only if clearly needed
  • Caution should be exercised when administered to nursing women

Precautions & Warnings

  • Use with caution and in reduced doses in patients with impaired hepatic or renal function
  • Caution in patients with epilepsy or a history of such disorders
  • Caution warranted in diabetic subjects
  • Careful supervision for depressed patients with suicidal tendencies
  • Not usually suitable for the depressive component of bipolar (manic depressive) illness

Pharmacology

  • Selectively inhibits the reuptake of serotonin at the presynaptic neuronal membrane
  • Causes increased synaptic concentration of serotonin in the CNS
  • No effect on the reuptake of norepinephrine and dopamine
  • Does not exhibit anticholinergic, antihistaminic or α1 adrenergic blocking activity at usual therapeutic doses

Storage Conditions

  • Protect from light and moisture
  • Store below 30°C
  • Keep in a cool and dry place
  • Keep out of the reach of children

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