Prodep 20 mg (Capsule)

Unit Price: ৳ 3.01 (10 x 10: ৳ 301.00)
Strip Price: ৳ 30.10

Medicine Details

Indications

  • depressive illness
  • bulimia nervosa
  • obsessive compulsive disorder

Pharmacology

  • selective inhibition of serotonin reuptake
  • increased synaptic concentration of serotonin
  • functional changes associated with enhanced serotonergic neurotransmission

Dosage & Administration

  • initial dose of 20 mg/day
  • dose increase after several weeks if no improvement
  • maximum dose of 80 mg/day
  • full antidepressant effect may be delayed until 4 weeks of treatment
  • lower or less frequent dosage for patients with renal and/or hepatic impairment
  • maintenance treatment for several months or longer
  • not recommended for use in children

Interaction

  • serious fatal reactions with MAO inhibitors
  • increase of stable plasma levels of other antidepressants
  • reports of increased or decreased lithium levels when used concomitantly
  • elevation of blood levels of certain antipsychotics and anticonvulsants
  • caution advised with concomitant administration of CNS active drugs

Contraindications

  • contraindicated in patients known to be hypersensitive to it
  • not to be used in combination with MAOIs or within 14 days of discontinuing therapy with MAOI
  • at least 5 weeks should be allowed after stopping before starting MAOI

Side Effects

  • gastrointestinal - nausea, vomiting, dyspepsia, dry mouth, diarrhoea
  • neurological - anxiety, nervousness, insomnia, drowsiness, fatigue
  • others - excessive sweating, pruritus, skin rashes associated with liver, kidney, and lung involvement

Pregnancy & Lactation

  • use in pregnancy only if clearly needed
  • caution should be exercised when administered to nursing women

Precautions & Warnings

  • use with caution in patients with impaired hepatic or renal function
  • use with caution in patients with epilepsy or a history of such disorders
  • caution warranted in diabetic subjects
  • careful supervision of depressed patients with suicidal tendencies
  • not usually considered a suitable form of therapy for the depressive component of bipolar illness

Therapeutic Class

  • Phenothiazine related drugs

Storage Conditions

  • protect from light & moisture
  • store below 30°C
  • keep in a cool & dry place
  • keep out of the reach of children

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