Parotin 10 mg (Tablet)

Unit Price: ৳ 6.04 (3 x 10: ৳ 181.20)
Strip Price: ৳ 60.40

Medicine Details

Category Details
Generic Paroxetine hydrochloride
Company Aci limited
Also available as
Parotin 20 mg tablet

Indications

  • Major Depressive Disorder
  • Obsessive Compulsive Disorder
  • Panic Disorder
  • Social Anxiety Disorder
  • Generalized Anxiety Disorder
  • Posttraumatic Stress Disorder

Pharmacology

Paroxetine potentiates serotonergic activity in the central nervous system by inhibiting neuronal reuptake of serotonin

Dosage & Administration

  • Major Depressive Disorder:
    • Initial Dose: 20 mg/day
    • Maximum Dose: 50 mg/day
    • Maintenance Therapy: 30 mg/day
  • Obsessive Compulsive Disorder (OCD):
    • Initial Dose: 20 mg/day
    • Maximum Dose: 40 mg/day
  • Panic Disorder:
    • Initial Dose: 10 mg/day
    • Maximum Dose: 60 mg/day
  • Social Anxiety Disorder (SAD):
    • Initial Dosage: 20 mg/day
  • Generalized Anxiety Disorder (GAD):
    • Starting Dosage: 20 mg/day
  • Posttraumatic Stress Disorder (PTSD):
    • Starting Dosage: 20 mg/day

Interaction

  • Absorption not affected by food or antacids
  • Potential interaction with tryptophan, drug metabolizing enzyme inducers/inhibitors, alcohol, haloperidol/amylobarbitone/oxazepam, MAOIs, lithium, phenytoin/anticonvulsants, warfarin

Contraindications

  • Concurrent use with MAOIs or thioridazine
  • Hypersensitivity to Paroxetine

Side Effects

  • Major depressive disorder:
    • Asthenia
    • Sweating
    • Nausea
    • Insomnia
    • Tremors
  • Obsessive compulsive disorder:
    • Nausea
    • Dry mouth
    • Tremor
    • Impotence
  • Panic disorder:
    • Asthenia
    • Sweating
    • Tremor
    • Impotence
  • Social anxiety disorder:
    • Sweating
    • Nausea
    • Dry mouth
    • Tremor
  • Generalised anxiety disorder:
    • Asthenia
    • Infection
    • Constipation
    • Nausea
  • Post-traumatic stress disorder:
    • Asthenia
    • Sweating
    • Nausea
    • Dry mouth

Pregnancy & Lactation

  • Use during pregnancy if benefit justifies risk
  • Caution with nursing mothers

Precautions & Warnings

  • Caution with cardiac conditions and epilepsy
  • Discontinue if seizures develop
  • Use with caution in patients with ECT

Use in Special Populations

  • Initial dose for elderly, debilitated, severe renal/hepatic impairment: 10 mg/day
  • Maximum Dose: 40 mg/day

Therapeutic Class

SSRIs & related anti-depressant drugs

Storage Conditions

Store at a cool and dry place, protect from light and moisture

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