Paroxet 20 mg (Tablet)

Unit Price: ৳ 9.06 (3 x 10: ৳ 271.80)
Strip Price: ৳ 90.60

Medicine Details

Indications

  • Major Depressive Disorder
  • Obsessive Compulsive Disorder
  • Panic Disorder
  • Social Anxiety Disorder
  • Generalized Anxiety Disorder
  • Posttraumatic Stress Disorder

Pharmacology

  • Potentiation of serotonergic activity
  • Inhibition of neuronal reuptake of serotonin
  • Selective inhibitor of neuronal serotonin reuptake
  • Little affinity for various receptors
  • Inhibition of muscarinic, histaminergic and alpha1-adrenergic receptors

Dosage & Administration

  • Usual Initial Dosage 20 mg/day
  • Maintenance Therapy dosage adjustments
  • 20 mg/day initial dose for various disorders
  • Dose changes at intervals of at least 1 week

Interaction

  • Absorption not affected by food or antacids
  • Potential interaction with Tryptophan
  • Affected by drug metabolizing enzyme inducers/inhibitors
  • Caution advised with alcohol and MAOIs
  • Potential interaction with lithium and anticonvulsants
  • Caution advised with warfarin

Contraindications

  • Concomitant use with MAOIs or thioridazine
  • Hypersensitivity to Paroxetine

Side Effects

  • Asthenia
  • Sweating
  • Nausea
  • Decreased appetite
  • Somnolence
  • Dizziness
  • Insomnia
  • Tremor
  • Nervousness
  • Ejaculatory disturbance
  • Dry mouth
  • Constipation
  • Decreased libido
  • Abnormal ejaculation
  • Impotence
  • Female genital disorders

Pregnancy & Lactation

  • Use only if potential benefit justifies potential risk to fetus
  • Caution with nursing mothers

Precautions & Warnings

  • Caution with cardiac conditions
  • Use with caution in patients with epilepsy
  • Discontinue if seizures develop
  • Use with caution in ECT
  • No impairment of cognitive or psychomotor function observed
  • Taper phase regimen for discontinuation of treatment
  • Recommended initial dose for special populations 10 mg/day

Use in Special Populations

  • Recommended initial dose for elderly, debilitated, severe renal or hepatic impairment 10 mg/day
  • Dosage should not exceed 40 mg/day

Therapeutic Class

  • SSRIs & related anti-depressant drugs

Storage Conditions

  • Keep out of the reach of children
  • Store at a cool and dry place
  • Protect from light and moisture

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