Chear 25 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Sertraline hydrochloride |
| Company | Aci limited |
| Also available as |
Indications
- Major depressive disorder (MDD)
- Obsessive-compulsive disorder (OCD)
- Panic disorder (PD)
- Post-traumatic stress disorder (PTSD)
- Social anxiety disorder (SAD)
- Premenstrual dysphoric disorder (PMDD)
Pharmacology
Potent and selective inhibitory action on CNS neuronal reuptake of 5-HT resulting in increased 5-HT concentrations at the synaptic clefts, leading to facilitation of its sustained activity at the postsynaptic receptor sites. Improvement of depression. Reduction of Serotonin turnover in brain.
Dosage & Administration
- Adults:
- Major depressive disorder:
- Starting Dose: 50 mg
- Therapeutic Range: 50-200 mg
- Obsessive-compulsive disorder:
- Starting Dose: 50 mg
- Therapeutic Range: 50-200 mg
- Panic disorder, Post-traumatic stress disorder, Social anxiety disorder:
- Starting Dose: 25 mg
- Therapeutic Range: 50-200 mg
- Major depressive disorder:
- Pediatric Patients (ages 6-12 years old):
- Obsessive-compulsive disorder:
- Starting Dose: 25 mg
- Therapeutic Range: 50-200 mg
- Obsessive-compulsive disorder:
- Premenstrual dysphoric disorder (PMDD):
- Starting Dosage: 50 mg/day
- Continuous: Patients not responding to a 50 mg dosage may benefit from dosage increases at 50 mg increments per menstrual cycle up to 150 mg per day.
- Intermittent: Patients not responding to a 50 mg dosage may benefit from increasing the dosage up to a maximum of 100 mg per day during the next menstrual cycle (and subsequent cycles).
- Recommended interval between dose changes: One week
Interaction
Potential effects of co-administration of drugs that are highly bound to plasma proteins. It may interact with drugs such as Cimetidine, CNS active drugs like Diazepam, Hypoglycemic drugs, Atenolol, etc.
Contraindications
Contraindicated in patients with a known hypersensitivity to Sertraline or any of the excipients of the drug. Not recommended in patients with moderate to severe hepatic impairment.
Side Effects
- Upset stomach
- Diarrhea
- Constipation
- Vomiting
- Dry mouth
- Loss of appetite
- Weight changes
- Drowsiness
- Dizziness
- Headache
- Pain
- Burning or tingling in the hands or feet
- Excitement
- Sore throat
Pregnancy & Lactation
Safety during human pregnancy has not been established. Known to be excreted in breast milk. Discontinuation of breast-feeding should be considered if treatment with Sertraline is necessary.
Precautions & Warnings
Precaution in case of liver problems, kidney diseases, seizures, heart problems, and any allergies. May cause dizziness or drowsiness. Caution should be taken in activities requiring alertness. Risk of suicidal thinking and change of behavior may occur.
Therapeutic Class
SSRIs & related anti-depressant drugs
Storage Conditions
Do not store above 30°C. Keep out of the reach of children.