Mudiral 25 mg (Tablet)
Unit Price: ৳ 3.01 (5 x 10: ৳ 150.50)
Strip Price: ৳ 30.10
Medicine Details
| Category | Details |
|---|---|
| Generic | Sertraline hydrochloride |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Major depressive disorder (MDD)
- Obsessive-compulsive disorder (OCD)
- Panic disorder (PD)
- Post-traumatic stress disorder (PTSD)
- Social anxiety disorder (SAD)
- Premenstrual dysphoric disorder (PMDD)
Pharmacology
- Potent and selective inhibitory action on CNS neuronal reuptake of 5-HT
- Increased 5-HT concentrations at the synaptic clefts
- Facilitation of sustained activity at the postsynaptic receptor sites
- Improvement of depression
- Reduction of Serotonin turnover in brain
- Prolonged elimination half-life for once daily administration
Dosage & Administration
- Starting doses for different disorders
- Therapeutic ranges for different disorders
- Recommended interval between dose changes
- Dosage for pediatric patients
- Continuous vs. intermittent dosage for PMDD
- Dosage adjustment for non-responding patients
Interaction
- Potential effects of co-administration of drugs highly bound to plasma proteins
- Adverse effects due to plasma protein displacement
- Interaction with specific drugs such as Cimetidine, Diazepam, Hypoglycemic drugs, Atenolol
Contraindications
- Hypersensitivity to Sertraline or excipients
- Moderate to severe hepatic impairment
Side Effects
- Upset stomach
- Diarrhoea
- Constipation
- Vomiting
- Dry mouth
- Loss of appetite
- Weight changes
- Drowsiness
- Dizziness
- Headache
- Pain
- Burning or tingling in the hands or feet
- Excitement
- Sore throat
Pregnancy & Lactation
- Teratogenicity evidence from animal studies
- Excretion in breast milk
- Impact on nursing infants
- Consideration of discontinuing breastfeeding if necessary
Precautions & Warnings
- Liver problems
- Kidney diseases
- Seizures
- Heart problems
- Allergies
- Dizziness or drowsiness
- Caution in activities requiring alertness
- Increased sensitivity in the elderly
- Avoiding monoamine oxidase inhibitors
- Risk of suicidal thinking and behavior
Therapeutic Class
- SSRIs & related anti-depressant drugs
Storage Conditions
- Temperature limitations (not above 30°C)
- Keep out of the reach of children