Repose 100 mg (Tablet)

Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00

Medicine Details

Category Details
Generic Sertraline hydrochloride
Company Incepta pharmaceuticals ltd
Also available as
Repose 25 mg tablet Repose 50 mg tablet

Indications

  • Major depressive disorder (MDD)
  • Obsessive-compulsive disorder (OCD)
  • Panic disorder (PD)
  • Post-traumatic stress disorder (PTSD)
  • Social anxiety disorder (SAD)
  • Premenstrual dysphoric disorder (PMDD)

Pharmacology

  • Potent and selective inhibitory action on CNS neuronal reuptake of 5-HT
  • Increased 5-HT concentrations at the synaptic clefts
  • Improvement of depression
  • Reduction of Serotonin turnover in the brain
  • Prolonged elimination half-life for once daily administration

Dosage & Administration

  • Starting dose for adults with major depressive disorder or obsessive-compulsive disorder: 50 mg
  • Therapeutic range for adults with major depressive disorder, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, and social anxiety disorder: 50-200 mg
  • Starting dose for pediatric patients (ages 6-12 years old) with obsessive-compulsive disorder: 25 mg
  • Recommended interval between dose changes: one week
  • Starting dosage for premenstrual dysphoric disorder (PMDD): 50 mg/day
  • Option for continuous or intermittent dosing for PMDD
  • Continuous dosage: patients not responding to a 50 mg dosage may benefit from dosage increases at 50 mg increments per menstrual cycle up to 150 mg per day
  • Intermittent dosage: patients not responding to a 50 mg dosage may benefit from increasing the dosage up to a maximum of 100 mg per day during the next menstrual cycle (and subsequent cycles)

Interaction

  • Potential effects of co-administration of drugs that are highly bound to plasma proteins
  • Possible interactions with drugs such as cimetidine, CNS active drugs, hypoglycemic drugs, atenolol, etc.

Contraindications

  • Known hypersensitivity to Sertraline or any of the excipients of the drug
  • Moderate to severe hepatic impairment

Side Effects

  • Upset stomach
  • Diarrhea
  • Constipation
  • Vomiting
  • Dry mouth
  • Loss of appetite
  • Weight changes
  • Drowsiness
  • Dizziness
  • Headache
  • Pain
  • Burning or tingling in the hands or feet
  • Excitement
  • Sore throat

Pregnancy & Lactation

  • Safety during human pregnancy not established
  • Excretion in breast milk
  • Discontinuation of breastfeeding should be considered if treatment is necessary

Precautions & Warnings

  • Liver problems
  • Kidney diseases
  • Seizures
  • Heart problems
  • Allergies
  • Dizziness or drowsiness
  • Caution in activities requiring alertness
  • Sensitivity of elderly to the effects of the drug
  • Avoidance if monoamine oxidase inhibitor taken in the last five weeks
  • Risk of suicidal thinking and changes in behavior

Therapeutic Class

  • SSRIs & related antidepressant drugs

Storage Conditions

  • Do not store above 30°C
  • Keep out of the reach of children

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