Setra 50 mg (Tablet)
Unit Price: ৳ 7.00 (5 x 10: ৳ 350.00)
Strip Price: ৳ 70.00
Medicine Details
Category | Details |
---|---|
Generic | Sertraline hydrochloride |
Company | General pharmaceuticals ltd |
Also available as |
Indications
- Major depressive disorder (MDD)
- Obsessive-compulsive disorder (OCD)
- Panic disorder (PD)
- Post-traumatic stress disorder (PTSD)
- Social anxiety disorder (SAD)
- Premenstrual dysphoric disorder (PMDD)
Pharmacology
Sertraline has potent and selective inhibitory action on CNS neuronal reuptake of 5-HT resulting in increased 5-HT concentrations at the synaptic clefts, leading to facilitation of its sustained activity at the postsynaptic receptor sites.
Dosage & Administration
- Adults:
- Starting Dose: 50 mg
- Therapeutic Range: 50-200 mg
- Pediatric Patients (ages 6-12 years old):
- Starting Dose: 25 mg
- Therapeutic Range: 50-200 mg
- Premenstrual dysphoric disorder (PMDD):
- Starting dosage for PMDD is 50 mg/day
- Continuous/Intermittent dosing options
Interaction
Potential effects of co-administration of drugs that are highly bound to plasma proteins. Setra may interact with other drugs such as Cimetidine, CNS active drugs like Diazepam, Hypoglycemic drugs, Atenolol etc.
Contraindications
- Known hypersensitivity to Sertraline or any of the excipients of drug
- Moderate to severe hepatic impairment
Side Effects
- Upset stomach
- Diarrhoea
- Constipation
- Vomiting
- Dry mouth
- Loss of appetite
- Weight changes
- Drowsiness
- Dizziness
- Headache
- Pain
- Burning or tingling in the hands or feet
- Excitement
- Sore throat
Pregnancy & Lactation
Although animal studies did not provide any evidence of teratogenicity, the safety of Sertraline during human pregnancy has not been established. Sertraline is known to be excreted in breast milk.
Precautions & Warnings
- Liver problems
- Kidney diseases
- Seizures
- Heart problems
- Allergies
- Dizziness or drowsiness
- Caution in activities requiring alertness
- Elderly use caution
- Do not take with monoamine oxidase inhibitor
- Risk of suicidal thinking and change of behavior
Therapeutic Class
SSRIs & related anti-depressant drugs
Storage Conditions
Do not store above 30°C. Keep out of the reach of children.