Setra 50 mg (Tablet)

Unit Price: ৳ 7.00 (5 x 10: ৳ 350.00)
Strip Price: ৳ 70.00

Medicine Details

Indications

  • Major depressive disorder (MDD)
  • Obsessive-compulsive disorder (OCD)
  • Panic disorder (PD)
  • Post-traumatic stress disorder (PTSD)
  • Social anxiety disorder (SAD)
  • Premenstrual dysphoric disorder (PMDD)

Pharmacology

Sertraline has potent and selective inhibitory action on CNS neuronal reuptake of 5-HT resulting in increased 5-HT concentrations at the synaptic clefts, leading to facilitation of its sustained activity at the postsynaptic receptor sites.

Dosage & Administration

  • Adults:
    • Starting Dose: 50 mg
    • Therapeutic Range: 50-200 mg
  • Pediatric Patients (ages 6-12 years old):
    • Starting Dose: 25 mg
    • Therapeutic Range: 50-200 mg
  • Premenstrual dysphoric disorder (PMDD):
    • Starting dosage for PMDD is 50 mg/day
    • Continuous/Intermittent dosing options

Interaction

Potential effects of co-administration of drugs that are highly bound to plasma proteins. Setra may interact with other drugs such as Cimetidine, CNS active drugs like Diazepam, Hypoglycemic drugs, Atenolol etc.

Contraindications

  • Known hypersensitivity to Sertraline or any of the excipients of drug
  • Moderate to severe hepatic impairment

Side Effects

  • Upset stomach
  • Diarrhoea
  • Constipation
  • Vomiting
  • Dry mouth
  • Loss of appetite
  • Weight changes
  • Drowsiness
  • Dizziness
  • Headache
  • Pain
  • Burning or tingling in the hands or feet
  • Excitement
  • Sore throat

Pregnancy & Lactation

Although animal studies did not provide any evidence of teratogenicity, the safety of Sertraline during human pregnancy has not been established. Sertraline is known to be excreted in breast milk.

Precautions & Warnings

  • Liver problems
  • Kidney diseases
  • Seizures
  • Heart problems
  • Allergies
  • Dizziness or drowsiness
  • Caution in activities requiring alertness
  • Elderly use caution
  • Do not take with monoamine oxidase inhibitor
  • Risk of suicidal thinking and change of behavior

Therapeutic Class

SSRIs & related anti-depressant drugs

Storage Conditions

Do not store above 30°C. Keep out of the reach of children.

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