Setra 100 mg (Tablet)
Unit Price: ৳ 11.00 (4 x 10: ৳ 440.00)
Strip Price: ৳ 110.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sertraline hydrochloride |
| Company | General pharmaceuticals ltd |
| Also available as |
Title
Setra Medicine
Categories
- Medicine
- Antidepressant
- Psychotropic Drug
- Pharmaceutical
Description
Setra is an anti-depressant medicine used to treat major depressive disorder, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, social anxiety disorder, and premenstrual dysphoric disorder.
Attributes
- Indications:
- Major depressive disorder (MDD)
- Obsessive-compulsive disorder (OCD)
- Panic disorder (PD)
- Post-traumatic stress disorder (PTSD)
- Social anxiety disorder (SAD)
- Premenstrual dysphoric disorder (PMDD)
- Mode of Action: Sertraline has potent and selective inhibitory action on CNS neuronal reuptake of 5-HT resulting in increased 5-HT concentrations at the synaptic clefts, leading to facilitation of its sustained activity at the postsynaptic receptor sites. It ultimately results in an improvement of depression. Reduction of Serotonin turnover in brain by Sertraline is also another contributing fact implicated in its action.
- Dosage & Administration:
- Adults:
- Major depressive disorder:
- Starting Dose: 50 mg
- Therapeutic Range: 50-200 mg
- Obsessive-compulsive disorder:
- Starting Dose: 50 mg
- Therapeutic Range: 50-200 mg
- Panic disorder, Post-traumatic stress disorder, Social anxiety disorder:
- Starting Dose: 25 mg
- Therapeutic Range: 50-200 mg
- Premenstrual dysphoric disorder (PMDD):
- Continuous: Starting dosage for PMDD is 50 mg/day. Patients not responding to a 50 mg dosage may benefit from dosage increases at 50 mg increments per menstrual cycle up to 150 mg per day.
- Intermittent: Starting the daily dosage 14 days prior to the anticipated onset of menstruation and continuing through the onset of menses. Patients not responding to a 50 mg dosage may benefit from increasing the dosage up to a maximum of 100 mg per day.
- Major depressive disorder:
- Pediatric Patients (ages 6-12 years old):
- Obsessive-compulsive disorder:
- Starting Dose: 25 mg
- Therapeutic Range: 50-200 mg
- Obsessive-compulsive disorder:
- Adults:
- Interaction: Potential effects of co-administration of drugs that are highly bound to plasma proteins. Setra may interact with drugs such as Cimetidine, CNS active drugs like Diazepam, Hypoglycemic drugs, Atenolol, etc.
- Contraindications:
- Known hypersensitivity to Sertraline or any of the excipients of the drug
- Moderate to severe hepatic impairment
- Side Effects:
- Upset stomach
- Diarrhoea
- Constipation
- Vomiting
- Dry mouth
- Loss of appetite
- Weight changes
- Drowsiness
- Dizziness
- Headache
- Pain
- Burning or tingling in the hands or feet
- Excitement
- Sore throat
- Pregnancy & Lactation: Although animal studies did not provide any evidence of teratogenicity, the safety of Sertraline during human pregnancy has not been established. Sertraline is known to be excreted in breast milk. If treatment with Sertraline is considered necessary, discontinuation of breastfeeding should be considered.
- Precautions & Warnings:
- Conditions to be cautious about:
- Liver problems
- Kidney diseases
- Seizures
- Heart problems
- Allergies
- Cautionary effects: Setra may cause dizziness or drowsiness. Caution should be taken in activities requiring alertness such as driving or using machinery. Caution is advised while using Setra in the elderly, and risk of suicidal thinking and change of behavior may occur.
- Avoidable actions: Do not take Setra if you have taken monoamine oxidase inhibitor in the last five weeks.
- Conditions to be cautious about:
- Therapeutic Class: SSRIs & related anti-depressant drugs
- Storage Conditions: Do not store above 30°C. Keep out of the reach of children.