Tralin 25 mg (Tablet)

Unit Price: ৳ 2.51 (10 x 10: ৳ 251.00)

Strip Price: ৳ 25.10

Medicine Details

Category	Details
Generic	Sertraline hydrochloride
Company	Silva pharmaceuticals ltd
Also available as	Tralin 50 mg tablet Tralin 100 mg tablet

Indications

Major depressive disorder (MDD)
Obsessive-compulsive disorder (OCD)
Panic disorder (PD)
Post-traumatic stress disorder (PTSD)
Social anxiety disorder (SAD)
Premenstrual dysphoric disorder (PMDD)

Pharmacology

Sertraline has potent and selective inhibitory action on CNS neuronal reuptake of 5-HT resulting in increased 5-HT concentrations at the synaptic clefts, leading to facilitation of its sustained activity at the postsynaptic receptor sites.

Dosage & Administration

Adults:
- Major depressive disorder:
  - Starting Dose: 50 mg
  - Therapeutic Range: 50-200 mg
- Obsessive-compulsive disorder:
  - Starting Dose: 50 mg
  - Therapeutic Range: 50-200 mg
- Panic disorder, Post-traumatic stress disorder, Social anxiety disorder:
  - Starting Dose: 25 mg
  - Therapeutic Range: 50-200 mg
Pediatric Patients (ages 6-12 years old):
- Obsessive-compulsive disorder:
  - Starting Dose: 25 mg
  - Therapeutic Range: 50-200 mg
Premenstrual dysphoric disorder (PMDD):
- Starting dosage: 50 mg/day
- Continuous: Patients not responding to a 50 mg dosage may benefit from dosage increases at 50 mg increments per menstrual cycle up to 150 mg per day.
- Intermittent: Patients not responding to a 50 mg dosage may benefit from increasing the dosage up to a maximum of 100 mg per day during the next menstrual cycle (and subsequent cycles).
Recommended Interval: One week

Interaction

Potential effects of co-administration of drugs that are highly bound to plasma proteins, Tralin may interact with other drugs such as Cimetidine, CNS active drugs like Diazepam, Hypoglycemic drugs, Atenolol etc.

Contraindications

Sertraline is contraindicated in patients with a known hypersensitivity to Sertraline or any of the excipients of drug. In patients with moderate to severe hepatic impairment is not recommended.

Side Effects

Upset stomach
Diarrhoea
Constipation
Vomiting
Dry mouth
Loss of appetite
Weight changes
Drowsiness
Dizziness
Headache
Pain
Burning or tingling in the hands or feet
Excitement
Sore throat

Pregnancy & Lactation

The safety of Sertraline during human pregnancy has not been established. Sertraline is known to be excreted in breast milk. If treatment with Sertraline is considered necessary, discontinuation of breast-feeding should be considered.

Precautions & Warnings

Conditions to be cautious about:
- Liver problems
- Kidney diseases
- Seizures
- Heart problems
- Any allergies
Caution effects: Dizziness or drowsiness, activities requiring alertness, elderly sensitivity, avoid after taking monoamine oxidase inhibitor, risk of suicidal thinking and change of behavior