Tralin 100 mg (Tablet)

Unit Price: ৳ 7.03 (5 x 10: ৳ 351.50)

Strip Price: ৳ 70.30

Medicine Details

Category	Details
Generic	Sertraline hydrochloride
Company	Silva pharmaceuticals ltd
Also available as	Tralin 25 mg tablet Tralin 50 mg tablet

Indications

Major depressive disorder (MDD)
Obsessive-compulsive disorder (OCD)
Panic disorder (PD)
Post-traumatic stress disorder (PTSD)
Social anxiety disorder (SAD)
Premenstrual dysphoric disorder (PMDD)

Pharmacology

Potent and selective inhibitory action on CNS neuronal reuptake of 5-HT resulting in increased 5-HT concentrations at the synaptic clefts, leading to facilitation of its sustained activity at the postsynaptic receptor sites.

Dosage & Administration

Adults:
- Major depressive disorder:
  - Starting Dose: 50 mg
  - Therapeutic Range: 50-200 mg
- Obsessive-compulsive disorder:
  - Starting Dose: 50 mg
  - Therapeutic Range: 50-200 mg
- Panic disorder, Post-traumatic stress disorder, Social anxiety disorder:
  - Starting Dose: 25 mg
  - Therapeutic Range: 50-200 mg
Pediatric Patients (ages 6-12 years old):
- Obsessive-compulsive disorder:
  - Starting Dose: 25 mg
  - Therapeutic Range: 50-200 mg
Premenstrual dysphoric disorder (PMDD):
- Starting dosage: 50 mg/day
- Continuous:
  - Patients not responding to a 50 mg dosage may benefit from dosage increases at 50 mg increments per menstrual cycle up to 150 mg per day.
- Intermittent:
  - Patients not responding to a 50 mg dosage may benefit from increasing the dosage up to a maximum of 100 mg per day during the next menstrual cycle (and subsequent cycles).

Interaction

Potential effects of co-administration of drugs that are highly bound to plasma proteins. May interact with drugs such as Cimetidine, diazepam, hypoglycemic drugs, atenolol, etc.

Contraindications

Contraindicated in patients with a known hypersensitivity to Sertraline or any of the excipients of the drug. Not recommended in patients with moderate to severe hepatic impairment.

Side Effects

Upset stomach
Diarrhoea
Constipation
Vomiting
Dry mouth
Loss of appetite
Weight changes
Drowsiness
Dizziness
Headache
Pain
Burning or tingling in the hands or feet
Excitement
Sore throat

Pregnancy & Lactation

Safety during human pregnancy has not been established. Known to be excreted in breast milk. Discontinuation of breast-feeding should be considered if treatment is necessary.

Precautions & Warnings

Caution in case of liver problems, kidney diseases, seizures, heart problems, and any allergies
May cause dizziness or drowsiness
Caution in activities requiring alertness such as driving or using machinery
Elderly may be more sensitive to the effects of the drug
Do not take Tralin if you have taken monoamine oxidase inhibitor in the last five weeks
Risk of suicidal thinking and change of behavior may occur, close monitoring required after 2 to 3 weeks of use