Zosert 50 mg (Tablet)
Unit Price: ৳ 6.02 (5 x 10: ৳ 301.00)
Strip Price: ৳ 60.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Sertraline hydrochloride |
| Company | Sun pharmaceutical bangladesh ltd |
| Also available as |
Title
- Zosert
Categories
- Medicine
- Anti-depressant
- SSRI
Description
- An anti-depressant medication indicated for Major depressive disorder (MDD), Obsessive-compulsive disorder (OCD), Panic disorder (PD), Post-traumatic stress disorder (PTSD), Social anxiety disorder (SAD), Premenstrual dysphoric disorder (PMDD)
Indications
- Major depressive disorder (MDD)
- Obsessive-compulsive disorder (OCD)
- Panic disorder (PD)
- Post-traumatic stress disorder (PTSD)
- Social anxiety disorder (SAD)
- Premenstrual dysphoric disorder (PMDD)
Pharmacology
- Potent and selective inhibitory action on CNS neuronal reuptake of 5-HT
- Increased 5-HT concentrations at the synaptic clefts
- Facilitation of sustained activity at the postsynaptic receptor sites
- Improvement of depression
- Reduction of Serotonin turnover in brain by Sertraline
Dosage & Administration
- Adults: Starting Dose - 25 mg to 50 mg
- Adults: Therapeutic Range - 50 mg to 200 mg
- Pediatric Patients (ages 6-12 years old): Starting Dose - 25 mg
- Pediatric Patients (ages 6-12 years old): Therapeutic Range - 50 mg to 200 mg
- Recommended interval between dose changes is one week
- PMDD Starting dosage - 50 mg/day, Intermittent dosing may be repeated
Interaction
- Potential effects of co-administration of drugs that are highly bound to plasma proteins
- Interaction with Cimetidine, CNS active drugs like Diazepam, Hypoglycemic drugs, Atenolol etc.
Contraindications
- Known hypersensitivity to Sertraline or any of the excipients of the drug
- Not recommended in patients with moderate to severe hepatic impairment
Side Effects
- Upset stomach
- Diarrhoea
- Constipation
- Vomiting
- Dry mouth
- Loss of appetite
- Weight changes
- Drowsiness
- Dizziness
- Headache
- Pain
- Burning or tingling in the hands or feet
- Excitement
- Sore throat
Pregnancy & Lactation
- Safety during human pregnancy not established
- Excreted in breast milk
- Discontinuation of breast-feeding should be considered if treatment is necessary
Precautions & Warnings
- Caution in case of liver problems, kidney diseases, seizures, heart problems and any allergies
- May cause dizziness or drowsiness
- Caution in activities requiring alertness such as driving or using machinery
- Caution in the elderly
- Do not take Zosert if monoamine oxidase inhibitor has been taken in the last five weeks
- Close monitoring of the patient after 2 to 3 weeks of use is required for risk of suicidal thinking and change of behavior
Therapeutic Class
- SSRIs & related anti-depressant drugs
Storage Conditions
- Do not store above 30°C
- Keep out of the reach of children