Depnox SR 150 mg (Tablet (Sustained Release))

Unit Price: ৳ 10.06 (30's pack: ৳ 301.75)

Medicine Details

Category	Details
Generic	Bupropion hydrochloride
Company	Jayson pharmaceuticals ltd

Selective inhibitor of neuronal re-uptake of catecholamines
Minimal effect on re-uptake of serotonin
May alter seizure threshold
Indicated in the treatment of depression and smoking cessation
Usual adult target dose is 300 mg/day
Dosage should begin at 150 mg/day and may be increased to 300 mg/day
Full antidepressant effect may not be evident until 4 weeks of treatment
Recommended lowest dose for maintenance of remission
Not recommended for child and adolescent under 18 years of age
Should not be given concurrently with or within 14 days of MAOI
Interactions with various drugs like alcohol, antimalarials, antipsychotics, etc.
Contraindicated in patients with a seizure disorder, bulimia, anorexia nervosa, and allergic response to Bupropion
Common side effects include agitation, anxiety, insomnia, dry mouth, headache, nausea, and skin rashes
Pregnancy Category C, excretion in human milk, decision on breastfeeding or drug discontinuation should be made
Use with extreme caution in patients with history of seizure disorders, severe hepatic cirrhosis, CNS tumor, bipolar depression, psychoses, recent history of myocardial infarction or unstable heart disease, and hepatic or renal impairment
Therapeutic class of atypical anti-depressant drugs
Storage conditions: Keep below 30°C temperature, away from light & moisture, and out of the reach of children

Usual adult target dose is 300 mg/day
Dosage should begin at 150 mg/day and may be increased to 300 mg/day
Full antidepressant effect may not be evident until 4 weeks of treatment
Increase in dosage to the maximum of 400 mg/day may be considered for patients with no clinical improvement at 300 mg/day
Lowest dose that maintains remission is recommended
Acute episodes of depression may require several months or longer of antidepressant drug treatment
Not recommended for child and adolescent under 18 years of age

Should not be given concurrently with or within 14 days of MAOI
Use of alcohol should be minimized or avoided completely
Interaction with various drugs such as antimalarials, antipsychotics, Quinolones, Tramadol, etc.

Contraindicated in patients with a seizure disorder
Contraindicated in patients with a current or prior diagnosis of bulimia or anorexia nervosa
Concurrent administration with MAO inhibitor is contraindicated
Contraindicated in patients who have shown an allergic response to Bupropion or its ingredients

Use with extreme caution in patients with history of seizure disorders
Use with caution in patients with bipolar depression or psychoses
Use with caution in patients with a recent history of myocardial infarction or unstable heart disease
Use with caution in patients with hepatic or renal impairment