Mirtaz 30 mg (Tablet)

Unit Price: ৳ 18.00 (5 x 10: ৳ 900.00)
Strip Price: ৳ 180.00

Medicine Details

Indications

  • Indicated for the treatment of major depressive disorder (MDD)

Pharmacology

  • Enhances central noradrenergic and serotonergic activity
  • Acts as an antagonist at central presynaptic α2-adrenergic inhibitory autoreceptors and heteroreceptors
  • Potent antagonist of 5- HT2 and 5-HT3 receptors
  • Moderate peripheral α1-adrenergic antagonist
  • Moderate antagonist at muscarinic receptors
  • Potent antagonist of histamine (H1) receptors

Dosage & Administration

  • Recommended starting dose is 15 mg/day
  • Effective dose range is 15 to 45 mg/day
  • Elimination half-life of approximately 20 to 40 hours
  • Dose changes should be made at intervals of less than 1 to 2 weeks

Interaction

  • Clinically significant drug-drug interactions with Monoamine Oxidase Inhibitors (MAOI) & other serotonergic drugs
  • May interrupt the metabolism or activity of Carbamazepine, Phenytoin or Cimetidine
  • Patients should avoid Alcohol & Diazepam while taking Mirtaz

Contraindications

  • Contraindicated in patients with a known hypersensitivity to Mirtazapine or to any of the excipients
  • Concomitant use of Mirtazapine and a monoamine oxidase (MAO) inhibitor is contraindicated

Side Effects

  • Common side effects include dizziness, drowsiness, dry mouth, increased appetite, weight gain

Pregnancy & Lactation

  • Pregnancy Category-C

Precautions & Warnings

  • Patients, their families, and their caregivers should be encouraged to be alert to the emergence of various behavioral changes
  • Patients who are to receive Mirtaz should be warned about the risk of developing agranulocytosis
  • Mirtaz may impair judgment, thinking, and motor skills

Therapeutic Class

  • Atypical anti-depressant drugs

Storage Conditions

  • Keep away from light and moisture
  • Store below 30° C
  • Keep all medicine out of the reach of children

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