Avert 50 mg (Tablet)

Indications

• Nausea
• Vomiting
• Motion sickness
• Vertigo

Pharmacology

• Antiemetic
• Anticholinergic
• Antihistaminic
• Sensitivity reduction of the labyrinthine apparatus
• Nerve pathways to the vomiting center
• Onset of action of 30-60 minutes
• Duration of action of 12-24 hours

Dosage & Administration

• Adult dosage: 25-50 mg once daily
• Motion sickness dosage: 25-50 mg 1 hour prior to travel, repeat every 24 hours if needed
• Vertigo dosage: 25-100 mg daily in divided doses
• Radiotherapy induced nausea and vomiting: 50 mg two to twelve hours prior to radiotherapy
• Emergency contraception: 25-50 mg 1 hour before first dose, repeat if needed in 24 hours
• Children dosage: Age 6-12 years, 12.5 mg once daily; Age 2-6 years, 6.25 mg once daily
• No clinical studies in children, use in elderly should be determined by physician

Interaction

• May increase toxicity with CNS depressants, neuroleptics, and anticholinergic
• Alcohol, sedatives, and tranquilizers can increase patient drowsiness

Contraindications

• Hypersensitivity to Meclizine or any of its excipients

Side Effects

• Drowsiness
• Dry mouth
• Blurred vision (rare)

Pregnancy & Lactation

• No risk of birth defects or abnormalities during pregnancy
• Excretion into milk, causes no harm to nursing babies

Precautions & Warnings

• Caution in patients with asthma, bronchitis, emphysema, enlarged prostate, glaucoma, or urinary tract blockage

Overdose Effects

• Symptoms: Extreme excitability, seizures, drowsiness, hallucinations
• Treatment: Appropriate supportive and symptomatic treatment, consider dialysis

Therapeutic Class

• Anti-emetic drugs

Storage Conditions

• Store in a cool & dry place, away from children

Related Brands

• Acliz 50 mg (Chewable Tablet) - aristopharma-ltd