Epazel (175 mg+225 mg)/5 ml (Oral Suspension)

200 ml bottle: ৳ 75.00

Medicine Details

Category	Details
Generic	Aluminium hydroxide magnesium hydroxide
Company	Edruc limited

Indications

Hyperacidity
Peptic ulcer
Gastritis
Heartburn
Sour stomach
Dyspepsia

Composition

Aluminium Hydroxide Gel BP (Al2O3 47%, minimum): 250 mg
Magnesium Hydroxide BP: 400 mg
Aluminium Oxide (Equivalent amount of Aluminium Hydroxide Gel USP): 175 mg
Magnesium Hydroxide (Equivalent amount of Magnesium Hydroxide Paste USP): 225 mg

Pharmacology

Well-balanced combination of essential non-systemic antacids without acid rebound, constipating or cathartic effects. Provides symptomatic relief of hyperacidity associated with heartburn, acid ingestion, or sour stomach. Aluminium hydroxide gel has high neutralizing power and prolonged effect. Magnesium Hydroxide possesses sustained acid neutralizing property. Both tablet and suspension possess adsorbent property and form a protecting coating over the ulcer surface, facilitating its healing.

Dosage & Administration

Tablet: Two tablets 1-3 hours after meal and at bedtime or as directed by the physician.
Suspension: 2 teaspoonful 1-3 hours after meal and at bedtime or as directed by the physician.

Interaction

Inhibits the absorption of drugs like Azithromycin, cefpodoxime, ciprofloxacin, isoniazid, rifampicin, norfloxacin, ofloxacin, pivampicillin, tetracyclines, Gabapentin, phenytoin, Itraconazole, ketoconazole, Chloroquine, hydroxychloroquine, and Phenothiazines.

Contraindications

Contraindicated in hypophosphataemia.
Contraindicated in alkalosis and hypermagnesaemia where abdominal distention may be due to partial or complete intestinal obstruction.

Side Effects

Long term use may result in alkaluria, predisposing to nephrolithiasis by forming precipitation of calcium phosphate.

Pregnancy & Lactation

Advised to avoid antacid preparations in the first trimester of pregnancy.

Precautions & Warnings

Antacids reduce the absorption of tetracycline when given concomitantly. Should not be used concomitantly.

Therapeutic Class

Antacids

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.