Maxocol 5 mg/5 ml (Syrup)
100 ml bottle: ৳ 15.77
Medicine Details
| Category | Details |
|---|---|
| Generic | Metoclopramide hydrochloride |
| Company | Medimet pharmaceuticals ltd |
| Also available as |
Indications
- Relief of symptoms in adults with acute and recurrent diabetic gastroparesis
- Treatment for symptomatic, documented gastroesophageal reflux in adults who fail to respond to conventional therapy
- Prevention of Nausea and Vomiting Associated with Emetogenic Cancer Chemotherapy
- Prevention of Postoperative Nausea and Vomiting
- Small Bowel Intubation
- Radiological Examination
Pharmacology
- Dopamine-2 (D2) antagonist
- Blocks serotonin receptors in chemoreceptor trigger zone of CNS
- Enhances the response to acetylcholine in the upper GI tract
- Enhanced motility and accelerated gastric emptying without stimulating gastric, biliary, or pancreatic secretions
- Increases lower esophageal sphincter tone
Dosage & Administration
- Recommended dosage for adults less than 65 years of age
- Recommended dosage for adults 65 years of age and older
- Continuous and intermittent administration for Gastroesophageal Reflux
- Dosage for Acute and Recurrent Diabetic Gastroparesis
- Dosage for the Relief of Symptoms Associated with Diabetic Gastroparesis
- Dosage for the Prevention of Nausea and Vomiting Associated with Emetogenic Cancer Chemotherapy
- Dosage for the Prevention of Postoperative Nausea and Vomiting
Contraindications
- History of tardive dyskinesia (TD) or a dystonic reaction
- Stimulation of gastrointestinal motility might be dangerous
- Pheochromocytoma or other catecholamine-releasing paragangliomas
- Epilepsy
- Hypersensitivity to metoclopramide
Side Effects
- Dysgeusia
- Headache
- Fatigue
Pregnancy & Lactation
- Pregnancy Category B
- Excretion in human milk
Precautions & Warnings
- Avoid concomitant use of other drugs known to cause TD/EPS/NMS
- Avoid use in patients with Parkinson’s Disease
- Discontinue and seek immediate medical attention if symptoms occur
- Avoid use in depression and suicidal ideation/suicide
Therapeutic Class
- Anti-emetic drugs
- Prokinetic drugs
Storage Conditions
- Store between 20-25°C
- Protect from light