Meclid 10 mg/2 ml (Injection)

2 ml ampoule: ৳ 3.77 (2 x 5: ৳ 37.70)

Medicine Details

Category	Details
Generic	Metoclopramide hydrochloride
Company	Jayson pharmaceuticals ltd

Relief of symptoms in adults with acute and recurrent diabetic gastroparesis
Treatment of symptomatic, documented gastroesophageal reflux in adults who fail to respond to conventional therapy
Prevention of nausea and vomiting associated with emetogenic cancer chemotherapy
Relief of symptoms associated with acute and recurrent diabetic gastric stasis

Metoclopramide blocks dopamine receptors
It blocks serotonin receptors in the chemoreceptor trigger zone of the CNS
Enhances the response to acetylcholine of tissue in the upper GI tract
Accelerates gastric emptying without stimulating gastric, biliary, or pancreatic secretions
Increases lower esophageal sphincter tone

Recommended dosage of 1 spray (15 mg) in one nostril for adults less than 65 years of age
Maximum of 4 sprays daily for 2 to 8 weeks, depending on symptomatic response
Administer 10 to 15 mg continuously or intermittently for gastroesophageal reflux
Administer 10 mg for acute and recurrent diabetic gastroparesis
Dosage for prevention of nausea and vomiting associated with emetogenic cancer chemotherapy
Usual adult dose for prevention of postoperative nausea and vomiting is 10 mg
Intravenous infusions should be made slowly over a period of not less than 15 minutes for cancer chemotherapy

Patients with a history of tardive dyskinesia (TD) or a dystonic reaction to metoclopramide
Stimulation of gastrointestinal motility might be dangerous in the presence of gastrointestinal hemorrhage, mechanical obstruction, or perforation
Patients with pheochromocytoma or other catecholamine-releasing paragangliomas
Patients with epilepsy
Patients with hypersensitivity to metoclopramide

Pregnancy Category B
Reproduction studies performed in rats, mice and rabbits have demonstrated no impairment of fertility or significant harm to the fetus due to metoclopramide
No adequate and well-controlled studies in pregnant women
The drug should be used during pregnancy only if clearly needed
Metoclopramide is excreted in human milk
Caution should be exercised when metoclopramide is administered to a nursing mother