Metocol 5 mg/5 ml (Syrup)
100 ml bottle: ৳ 15.83
Medicine Details
Category | Details |
---|---|
Generic | Metoclopramide hydrochloride |
Company | Opsonin pharma ltd |
Also available as |
Product Title
- Metoclopramide Nasal Spray
- Metoclopramide Tablet
- Metoclopramide Injection
Categories
- Medicine
- Gastrointestinal Medication
- Anti-Emetic
- Prokinetic
Description
- Indicated for relief of symptoms in adults with acute and recurrent diabetic gastroparesis
- Treatment for gastroesophageal reflux
- Blocks dopamine and serotonin receptors
- Enhances response to acetylcholine in upper GI tract
- Accelerates gastric emptying
- Increases lower esophageal sphincter tone
- Dosage varies by age and indication
- Contraindicated in certain medical conditions
- Pregnancy Category B
- Excreted in human milk
Color Options
- Transparent
Dosage Form
- Nasal Spray
- Tablet
- Injection
Age Group
- Adults less than 65 years
- Adults 65 years and older
Dosage Recommendations
- 1 spray (15 mg) in one nostril, 30 minutes before each meal and at bedtime
- Administer 10 to 15 mg, 30 minutes before each meal and at bedtime
- Doses of 10 mg administered slowly by the intravenous route over a 1- to 2-minute period
- Intravenous infusions slowly over a period of not less than 15 minutes
Symptoms Relief Duration
- 2 to 8 weeks
Medical Conditions
- Diabetic Gastroparesis
- Gastroesophageal Reflux
- Nausea and Vomiting Associated with Emetogenic Cancer Chemotherapy
- Postoperative Nausea and Vomiting
- Diabetic Gastric Stasis
- Mechanical Obstruction
- Perforation
- Pheochromocytoma
- Epilepsy
Contraindications
- History of tardive dyskinesia or a dystonic reaction to metoclopramide
- Gastrointestinal hemorrhage
- Pheochromocytoma or other catecholamine-releasing paragangliomas
- Epilepsy
- Hypersensitivity to metoclopramide
Side Effects
- Dysgeusia
- Headache
- Fatigue
Pregnancy Category
- B
Fertility Studies
- Performed in rats, mice, and rabbits
Storage Conditions
- Store between 20-25°C
- Protect from light
Pharmacological Action
- Blocks dopamine receptors
- Blocks serotonin receptors in higher doses
- Enhances response to acetylcholine in upper GI tract
- Increases lower esophageal sphincter tone
Usability
- Relief of symptoms in adults with diabetic gastroparesis
- Prevention of nausea and vomiting associated with chemotherapy
- Prevention of postoperative nausea and vomiting
Drug Classes
- Anti-Emetic
- Prokinetic
Precautions
- Avoid concomitant use of other drugs known to cause TD/EPS/NMS
- Avoid use in patients with Parkinson’s Disease
- Discontinue and seek medical attention if symptoms occur
- Avoid use in depression and suicidal ideation/suicide
Pharmacology
- Blocks dopamine receptors
- Also blocks serotonin receptors in higher doses
- Enhances response to acetylcholine
- Increases lower esophageal sphincter tone