Metocol 5 mg/5 ml (Syrup)

100 ml bottle: ৳ 15.83

Medicine Details

Product Title

  • Metoclopramide Nasal Spray
  • Metoclopramide Tablet
  • Metoclopramide Injection

Categories

  • Medicine
  • Gastrointestinal Medication
  • Anti-Emetic
  • Prokinetic

Description

  • Indicated for relief of symptoms in adults with acute and recurrent diabetic gastroparesis
  • Treatment for gastroesophageal reflux
  • Blocks dopamine and serotonin receptors
  • Enhances response to acetylcholine in upper GI tract
  • Accelerates gastric emptying
  • Increases lower esophageal sphincter tone
  • Dosage varies by age and indication
  • Contraindicated in certain medical conditions
  • Pregnancy Category B
  • Excreted in human milk

Color Options

  • Transparent

Dosage Form

  • Nasal Spray
  • Tablet
  • Injection

Age Group

  • Adults less than 65 years
  • Adults 65 years and older

Dosage Recommendations

  • 1 spray (15 mg) in one nostril, 30 minutes before each meal and at bedtime
  • Administer 10 to 15 mg, 30 minutes before each meal and at bedtime
  • Doses of 10 mg administered slowly by the intravenous route over a 1- to 2-minute period
  • Intravenous infusions slowly over a period of not less than 15 minutes

Symptoms Relief Duration

  • 2 to 8 weeks

Medical Conditions

  • Diabetic Gastroparesis
  • Gastroesophageal Reflux
  • Nausea and Vomiting Associated with Emetogenic Cancer Chemotherapy
  • Postoperative Nausea and Vomiting
  • Diabetic Gastric Stasis
  • Mechanical Obstruction
  • Perforation
  • Pheochromocytoma
  • Epilepsy

Contraindications

  • History of tardive dyskinesia or a dystonic reaction to metoclopramide
  • Gastrointestinal hemorrhage
  • Pheochromocytoma or other catecholamine-releasing paragangliomas
  • Epilepsy
  • Hypersensitivity to metoclopramide

Side Effects

  • Dysgeusia
  • Headache
  • Fatigue

Pregnancy Category

  • B

Fertility Studies

  • Performed in rats, mice, and rabbits

Storage Conditions

  • Store between 20-25°C
  • Protect from light

Pharmacological Action

  • Blocks dopamine receptors
  • Blocks serotonin receptors in higher doses
  • Enhances response to acetylcholine in upper GI tract
  • Increases lower esophageal sphincter tone

Usability

  • Relief of symptoms in adults with diabetic gastroparesis
  • Prevention of nausea and vomiting associated with chemotherapy
  • Prevention of postoperative nausea and vomiting

Drug Classes

  • Anti-Emetic
  • Prokinetic

Precautions

  • Avoid concomitant use of other drugs known to cause TD/EPS/NMS
  • Avoid use in patients with Parkinson’s Disease
  • Discontinue and seek medical attention if symptoms occur
  • Avoid use in depression and suicidal ideation/suicide

Pharmacology

  • Blocks dopamine receptors
  • Also blocks serotonin receptors in higher doses
  • Enhances response to acetylcholine
  • Increases lower esophageal sphincter tone

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