Nutramid 10 mg (Tablet)

Unit Price: ৳ 0.35 (100's pack: ৳ 35.00)

Medicine Details

Category Details
Generic Metoclopramide hydrochloride
Company Acme laboratories ltd
Also available as
Nutramid 1 mg pediatric drop Nutramid 5 mg syrup

Indications

  • Relief of symptoms in adults with acute and recurrent diabetic gastroparesis
  • Treatment for 4 to 12 weeks of symptomatic, documented gastroesophageal reflux in adults who fail to respond to conventional therapy
  • Prevention of nausea and vomiting associated with emetogenic cancer chemotherapy
  • Prevention of postoperative nausea and vomiting
  • Facilitates small bowel intubation in adults and pediatric patients
  • Stimulates gastric emptying and intestinal transit of barium for radiological examination

Pharmacology

  • Blocks dopamine receptors
  • Blocks serotonin receptors in chemoreceptor trigger zone of the CNS
  • Enhances the response to acetylcholine of tissue in upper GI tract
  • Accelerates gastric emptying without stimulating gastric, biliary, or pancreatic secretions
  • Increases lower esophageal sphincter tone

Dosage & Administration

  • Recommended dosage of 1 spray (15 mg) in one nostril, 30 minutes before each meal and at bedtime (maximum of 4 sprays daily) for 2 to 8 weeks
  • Alternate dosage for adults 65 years of age and older
  • Continuous administration of 10 to 15 mg, 30 minutes before each meal and at bedtime (maximum of 60 mg per day) for 4 to 12 weeks
  • Intermittent administration of up to 20 mg prior to provoking situation
  • Recommended dosage of 10 mg, 30 minutes before each meal and at bedtime (maximum of 40 mg per day) for 2 to 8 weeks
  • Intravenous infusions made slowly over a period of not less than 15 minutes
  • Intramuscular administration near the end of surgery

Contraindications

  • History of tardive dyskinesia (TD) or a dystonic reaction to metoclopramide
  • Stimulation of gastrointestinal motility might be dangerous
  • Presence of gastrointestinal hemorrhage, mechanical obstruction, or perforation
  • Presence of pheochromocytoma or other catecholamine-releasing paragangliomas
  • Epilepsy
  • Hypersensitivity to metoclopramide

Side Effects

  • Dysgeusia
  • Headache
  • Fatigue

Pregnancy & Lactation

  • Pregnancy Category B
  • No impairment of fertility or significant harm to the fetus demonstrated in animal studies
  • Excretion in human milk
  • Caution in nursing mothers

Precautions & Warnings

  • Avoid concomitant use of other drugs known to cause TD/EPS/NMS
  • Avoid use in patients with Parkinson’s Disease
  • Discontinue and seek immediate medical attention if TD/EPS/NMS symptoms occur
  • Avoid use in depression and suicidal ideation/suicide

Therapeutic Class

Anti-emetic drugs, Prokinetic drugs

Storage Conditions

Store between 20-25°C, protect from light

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