Anset 8 mg/4 ml (IM/IV Injection)
4 ml ampoule: ৳ 32.00 (2 x 5: ৳ 320.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ondansetron |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
- Prevention and treatment of post-operative nausea and vomiting
- Prevention of radiotherapy-induced nausea and vomiting
Description
- Orally dissolving film designed to be applied on top of the tongue and dissolve within 20 seconds
- Active ingredient: Anset base, a selective blocking agent of serotonin 5-HT3 receptor type
Pharmacology
- Selective 5HT3 receptor antagonist
- Mechanism of action involves antagonism of 5HT3 receptors in both peripheral and central nervous systems
Dosage
- Different doses for adults, pediatric patients, and geriatric patients based on the indication and type of treatment
- Oral tablets, orodispersible tablets, and injection formulations available
Administration
- Step-by-step guide for administering the oral soluble film
- No water required for dissolution or swallowing
Interaction
- Metabolized by hepatic cytochrome P-450 enzymes
- Inducers or inhibitors of these enzymes may affect clearance and half-life of the drug
Contraindications
- Hypersensitivity to the drug or its components
- Contraindicated with concomitant use of apomorphine
Side Effects
- Common adverse events include headache, constipation, and diarrhea
- Rare cases of anaphylaxis and tachycardia reported
Pregnancy & Lactation
- No evidence of harm in animal studies up to certain doses
- Limited data available for pregnant women, caution advised for nursing women
Precautions & Warnings
- Hypersensitivity reactions reported in some patients
- Not a gastric stimulant, should not be used for nasogastric suction
Use in Special Populations
- Dosage adjustments for patients with impaired renal or hepatic function
- Limited information available for pediatric patients 4 years of age or younger
Therapeutic Class
- Belongs to the therapeutic class of anti-emetic drugs
Storage Conditions
- Store below 30°C in a dry place
- Protect from light and moisture