Avona 4 mg/5 ml (Oral Solution)
50 ml bottle: ৳ 32.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ondansetron |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
- Prevention and treatment of post-operative nausea and vomiting
- Prevention of radiotherapy-induced nausea and vomiting
Dosage
- 8 mg tablet/orodispersible tablet for prevention of chemotherapy-induced nausea and vomiting
- 4 mg orodispersible tablet for prevention of chemotherapy-induced nausea and vomiting
- Injection for prevention of chemotherapy-induced nausea and vomiting
- 8 mg tablet/orodispersible tablet for prevention of radiotherapy-induced nausea and vomiting
- 4 mg orodispersible tablet for prevention of radiotherapy-induced nausea and vomiting
- Injection for prevention of radiotherapy-induced nausea and vomiting
- 8 mg tablet/orodispersible tablet for postoperative nausea and vomiting
- 4 mg orodispersible tablet for postoperative nausea and vomiting
- Injection for postoperative nausea and vomiting
- Oral Solution for highly emetogenic cancer chemotherapy
- Oral Solution for moderately emetogenic cancer chemotherapy
Mode of Action
- Selective blocking agent of the serotonin 5-HT3 receptor type
- Antagonism of 5HT3 receptors on neurons located in the peripheral and central nervous system
Administration
- Oral soluble film designed to be applied on top of the tongue
- Dissolves within 20 seconds
- No water required for dissolution or swallowing
- Can be swallowed with or without liquid
Interaction
Does not induce or inhibit the cytochrome P-450 drug-metabolizing enzyme system
Contraindications
- Hypersensitivity to the drug or any of its components
- Concomitant use of apomorphine
Side Effects
- Headache
- Constipation
- Diarrhea
- Rash
- Flushing or warmth
- Hiccups
- Liver enzyme abnormalities
- Anaphylaxis
- Bronchospasm
- Tachycardia
- Angina
- Hypokalemia
- Shortness of breath
- No evidence of extrapyramidal reactions
Pregnancy & Lactation
No adequate and well-controlled studies in pregnant women
Precautions & Warnings
- Hypersensitivity reactions reported
- Not a drug that stimulates gastric or intestinal peristalsis
- Should not be used instead of nasogastric suction
Therapeutic Class
Anti-emetic drugs
Storage Conditions
Store at temperature not exceeding 30°C in a dry place, protect from light and moisture