Emeren 8 mg (Tablet)
Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ondansetron |
| Company | Renata limited |
| Also available as |
Indications
- Prevention of nausea and vomiting associated with emetogenic cancer chemotherapy
- Prevention and treatment of post-operative nausea and vomiting
- Prevention of radiotherapy-induced nausea and vomiting
Oral Soluble Film
- Designed to dissolve within 20 seconds when applied on top of the tongue
- Does not require water for dissolution or swallowing
- Contains Emeren base as the active ingredient
- Composed of C18H19N3O with a molecular weight of 293.3
Pharmacology
- Acts as a potent, highly selective 5HT3 receptor-antagonist
- Blocks the initiation of vomiting reflex by activating 5HT3 receptors
- Antagonizes 5HT3 receptors in both peripheral and central nervous system
Dosage
- Available in 8mg and 4mg oral soluble tablet forms
- Recommended doses for both adults and pediatric patients
- Administration details for highly and moderately emetogenic cancer chemotherapy
- Dosage adjustment for patients with impaired renal and hepatic function
Administration
- Step by step guide for administering the oral soluble film
- Instructions for tearing the pouch, placing on tongue, and swallowing
Interaction
- Metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes
- No dosage adjustment recommended for patients on drugs inducing or inhibiting these enzymes
Contraindications
- Contraindicated in patients with known hypersensitivity to the drug or its components
- Concomitant use of apomorphine
Side Effects
- Frequently reported events include headache, constipation, and diarrhea
- Rare occurrences of rash, flushing, hiccups, and liver enzyme abnormalities
- Reported cases of anaphylaxis, tachycardia, chest pain, and shortness of breath
Pregnancy & Lactation
- No evidence of carcinogenic effects or mutagenicity in animal studies
- No impairment of fertility or harm to fetus in animal reproduction studies
- Caution advised in nursing women due to excretion of the drug in breast milk
Precautions & Warnings
- Caution for use in patients with hypersensitivity to 5HT3 receptor antagonists
- Not to be used in place of nasogastric suction
- Potential to mask progressive ileus and gastric distension
Use in Special Populations
- Dosage adjustment recommendations for patients with impaired renal and hepatic function
- Limited information available for pediatric patients 4 years of age or younger
Therapeutic Class
- Belongs to the class of anti-emetic drugs
Storage Conditions
- Store at temperatures not exceeding 30°C in a dry place
- Protection from light and moisture is recommended