Olmesafe 20 mg (Tablet)

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Olmesartan medoxomil
Company Orion pharma ltd
Also available as

Indications

  • Treatment of hypertension
  • May be used alone or in combination with other antihypertensive agents

Pharmacology

  • Blocks vasoconstrictor effects of angiotensin II
  • Selective binding of angiotensin II to AT 1 receptor in vascular smooth muscle
  • Does not inhibit ACE (kininase II)

Dosage & Administration

  • Usual recommended starting dose of 20 mg once daily
  • Daily dosage may be increased to 40 mg if further reduction in blood pressure is required
  • No initial dosage adjustment recommended for elderly patients or those with moderate to marked renal/hepatic impairment

Interaction

  • No significant drug interactions reported with digoxin or warfarin
  • Bioavailability not significantly altered by antacids
  • Potential renal function deterioration when co-administered with NSAIDs

Contraindications

  • Contraindicated in patients hypersensitive to any component of the product

Side Effects

  • Well tolerated with incidence of adverse reactions similar to placebo
  • Dizziness, back pain, increased creatine phosphokinase, diarrhea, headache, hyperglycemia, among the reported adverse reactions

Pregnancy & Lactation

  • Discontinue if pregnancy is detected
  • Drugs like Olmesartan can cause injury to developing fetus when used during second and third trimesters
  • Potential excretion in human milk with adverse effects on the nursing infant

Precautions & Warnings

  • Inhibiting the renin-angiotensin-aldosterone system may lead to changes in renal function
  • Oliguria, progressive azotemia, acute renal failure, and death are possible in susceptible individuals

Overdose Effects

  • Likely effects include hypotension and tachycardia
  • Clinically significant hypotension requires active support of the cardiovascular system

Therapeutic Class

Angiotensin-ll receptor blocker

Storage Conditions

Store below 30°C, protect from light & moisture

Chemical Structure

  • Molecular Formula: C29H30N6O6

Common Questions about Olmesafe 20 mg Tablet

  • Used to treat high blood pressure
  • Average time taken to reach peak effect is 1 day to 1 week
  • Generally used once or twice a day
  • Advised to be consumed orally
  • Stored at room temperature, away from heat and direct light
  • Quick tips for usage and precautions

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