Ondason 4 mg/5 ml (Oral Solution)

50 ml bottle: ৳ 45.00

Medicine Details

Indications

  • Prevention of nausea and vomiting associated with emetogenic cancer chemotherapy
  • Prevention and treatment of post-operative nausea and vomiting
  • Prevention of radiotherapy-induced nausea and vomiting

Type

Oral Soluble Film

Ingredients

Ondansetron base

Molecular Weight

293.3

Mode of Action

5HT3 receptor-antagonist

Dosage

  • 8 mg tablet/orodispersible tablet
  • 4 mg orodispersible tablet
  • Injection
  • Oral Solution

Administration

  • Oral intake as film that dissolves in 20 seconds
  • No need for water to aid dissolution or swallowing

Interaction

Metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes

Contraindications

  • Hypersensitivity to the drug or any of its components
  • Concomitant use of apomorphine

Side Effects

  • Headache
  • Constipation
  • Diarrhea
  • Rash
  • Sensation of flushing or warmth
  • Liver enzyme abnormalities
  • Anaphylaxis
  • Brochospasm
  • Tachycardia
  • Angina
  • Hypokalemia
  • Shortness of breath
  • Oculogyric crisis

Pregnancy & Lactation

  • No evidence of impaired fertility or harm to fetus in rats and rabbits
  • Excreted in breast milk of rats
  • Caution in nursing women

Precautions & Warnings

  • Hypersensitivity reactions
  • Not a drug that stimulates gastric or intestinal peristalsis
  • Should not be used instead of nasogastric suction
  • May mask a progressive ileus and/or gastric distension

Special Populations Dosage Adjustment

  • Renal Function
  • Hepatic Function
  • Pediatric
  • Elderly patients

Therapeutic Class

Anti-emetic drugs

Storage Conditions

Store at temperature not exceeding 30°C in a dry place. Protect from light and moisture

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