Premesis 8 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ondansetron |
| Company | Globe pharmaceuticals ltd |
| Also available as |
Indications
- Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
- Prevention and treatment of post-operative nausea and vomiting
- Prevention of radiotherapy-induced nausea and vomiting
Description
Orally dissolving film designed to be applied on top of the tongue and dissolve within 20 seconds
Pharmacology
- Selective blocking agent of the serotonin 5-HT3 receptor type
- Mechanism of action in the management of nausea and vomiting induced by cytotoxic chemotherapy and radiotherapy
Dosage
- Different doses for adults and pediatric patients
- Specific dosages for highly emetogenic and moderately emetogenic cancer chemotherapy
- Oral solution and oral soluble film administration details
Administration
- Step by step guide for administration of the oral soluble film
Interaction
- Does not induce or inhibit the cytochrome P-450 drug-metabolizing enzyme system
Contraindications
- Hypersensitivity to the drug or any of its components
- Concomitant use of apomorphine
Side Effects
- Frequently reported adverse events such as headache, constipation, diarrhea, and rash
- Rare cases of anaphylaxis, bronchospasm, tachycardia, angina, hypokalemia, and shortness of breath
Pregnancy & Lactation
- No evidence of impaired fertility or harm to the fetus in animal studies
- Excretion in breast milk, caution for nursing women
Precautions & Warnings
- Reported hypersensitivity reactions
- Not a drug that stimulates gastric or intestinal peristalsis
- Caution in patients with chemotherapy-induced nausea and vomiting
Use in Special Populations
- Dosage recommendation for patients with impaired renal function and hepatic function
- Limited information available for pediatric patients aged 4 years or younger
Therapeutic Class
Anti-emetic drugs
Storage Conditions
Store at temperature not exceeding 30°C in a dry place, protect from light and moisture